O-Benzyl Indacaterol

About O-Benzyl Indacaterol

O-Benzyl Indacaterol is an impurity of Indacaterol carrying the CAS registry number 435273-75-9. Formula C31H34N2O3, molecular weight 482.6 g/mol. The IUPAC name is 5-[(1R)-2-[(5,6-diethyl-2,3-dihydro-1H-inden-2-yl)amino]-1-hydroxyethyl]-8-phenylmethoxy-1H-quinolin-2-one. Alternative names: Benzyl Indacaterol and Indacaterol interMediate.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

As a characterised impurity of Indacaterol, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer O-Benzyl Indacaterol in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Indacaterol

View every impurity, metabolite and intermediate we list for Indacaterol.

Indacaterol impurities

Specifications & identifiers

Chemical identifiers
Product name	O-Benzyl Indacaterol
Catalogue No.	VQ-026158
CAS Number	435273-75-9
IUPAC name	5-[(1R)-2-[(5,6-diethyl-2,3-dihydro-1H-inden-2-yl)amino]-1-hydroxyethyl]-8-phenylmethoxy-1H-quinolin-2-one
Molecular formula	C₃₁H₃₄N₂O₃
Molecular weight	482.6 g/mol
Exact mass	482.2569
Grade	Reference Standard
HSN code	38229090
InChIKey	OTINTMLHLKCOBW-NDEPHWFRSA-N
SMILES	CCC1=C(C=C2CC(CC2=C1)NC[C@@H](C3=C4C=CC(=O)NC4=C(C=C3)OCC5=CC=CC=C5)O)CC
PubChem CID	23521613

Physical properties
Physical form	Solid
LogP (XLogP3)	5.2
H-bond donors / acceptors	3 / 4
TPSA	70.6 Å²
Synonyms	Benzyl Indacaterol, Indacaterol interMediate, 8-benzyloxy-5-[(R)-2-(5,6-diethyl-indan-2-ylamino)-1-hydroxy-ethyl]-1H-quinolin-2-one, (R)-8-(Benzyloxy)-5-[2-[(5,6-diethyl-2-indanyl)amino]-1-hydroxyethyl]quinolin-2(1H)-one, (r)-8-benzyloxy-5-[2-(5,6-diethyl-indan-2-ylamino)-1-hydroxy-ethyl]-1h-quinolin-2-one

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302+H312+H332Harmful if swallowed, in contact with skin or if inhaled
H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of O-Benzyl Indacaterol?

The CAS Registry Number of O-Benzyl Indacaterol is 435273-75-9. It is also known as Benzyl Indacaterol, Indacaterol interMediate, 8-benzyloxy-5-[(R)-2-(5,6-diethyl-indan-2-ylamino)-1-hydroxy-ethyl]-1H-quinolin-2-one.

What is the molecular formula and molecular weight of O-Benzyl Indacaterol?

O-Benzyl Indacaterol has the molecular formula C31H34N2O3 and a molecular weight of 482.6 g/mol. Its IUPAC name is 5-[(1R)-2-[(5,6-diethyl-2,3-dihydro-1H-inden-2-yl)amino]-1-hydroxyethyl]-8-phenylmethoxy-1H-quinolin-2-one.

What is O-Benzyl Indacaterol used for?

O-Benzyl Indacaterol is supplied as a characterised reference material related to Indacaterol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of O-Benzyl Indacaterol can I order?

We supply O-Benzyl Indacaterol in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with O-Benzyl Indacaterol?

Yes. Every lot of O-Benzyl Indacaterol is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can O-Benzyl Indacaterol be shipped internationally?

Yes. O-Benzyl Indacaterol is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.