Harmine

About Harmine

Harmine is a high-purity reference standard of Harmine carrying the CAS registry number 442-51-3. The compound has the formula C13H12N2O, corresponding to a molecular weight of 212.25 g/mol. Its systematic (IUPAC) name is 7-methoxy-1-methyl-9H-pyrido[3,4-b]indole. It is also known as Banisterine or Telepathine.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

As a reference sample of Harmine, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Harmine is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Harmine

View every impurity, metabolite and intermediate we list for Harmine.

Harmine impurities

Specifications & identifiers

Chemical identifiers
Product name	Harmine
Catalogue No.	VQ-032967
CAS Number	442-51-3
IUPAC name	7-methoxy-1-methyl-9H-pyrido[3,4-b]indole
Molecular formula	C₁₃H₁₂N₂O
Molecular weight	212.25 g/mol
Exact mass	212.095
Grade	Reference Standard
HSN code	38229090
InChIKey	BXNJHAXVSOCGBA-UHFFFAOYSA-N
SMILES	CC1=NC=CC2=C1NC3=C2C=CC(=C3)OC
PubChem CID	5280953

Physical properties
Physical form	Solid
LogP (XLogP3)	3.6
H-bond donors / acceptors	1 / 2
TPSA	37.9 Å²
Synonyms	Banisterine, Telepathine, Leucoharmine, Yageine, Yajeine, 9H-Pyrido[3,4-b]indole, 7-methoxy-1-methyl-, 1-Methyl-7-methoxy-beta-carboline, 7-Methoxy-1-methyl-9H-pyrido(3,4-b)indole, 9H-Pyrido(3,4-b)indole, 7-methoxy-1-methyl-, 7-Methoxy-1-methyl-9H-beta-carboline, Harmin, Harmine (Telepathine)

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302+H312+H332Harmful if swallowed, in contact with skin or if inhaled
H302Harmful if swallowed
H312Harmful in contact with skin
H319Causes serious eye irritation
H332Harmful if inhaled

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P321, P330, P337 + P317, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Harmine?

The CAS Registry Number of Harmine is 442-51-3. It is also known as Banisterine, Telepathine, Leucoharmine.

What is the molecular formula and molecular weight of Harmine?

Harmine has the molecular formula C13H12N2O and a molecular weight of 212.25 g/mol. Its IUPAC name is 7-methoxy-1-methyl-9H-pyrido[3,4-b]indole.

What is Harmine used for?

Harmine is supplied as a characterised reference material related to Harmine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Harmine can I order?

We supply Harmine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Harmine?

Yes. Every lot of Harmine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Harmine be shipped internationally?

Yes. Harmine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.