Cyclopamine

Name: Cyclopamine
Brand: Vaqora Chemicals
SKU: VQ-047885

About Cyclopamine

Cyclopamine is an API reference standard carrying the CAS registry number 4449-51-8. With the molecular formula C27H41NO2, it has a molar mass of 411.6 g/mol. It is also known as 11-Deoxojervine or 11-Deoxyjervine.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Warning” with 2 hazard statements. Review the Safety Data Sheet before use.

As a reference sample of the parent drug substance, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Cyclopamine in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Specifications & identifiers

Chemical identifiers
Product name	Cyclopamine
Catalogue No.	VQ-047885
CAS Number	4449-51-8
IUPAC name	(3S,3'R,3'aS,6'S,6aS,6bS,7'aR,9R,11aS,11bR)-3',6',10,11b-tetramethylspiro[2,3,4,6,6a,6b,7,8,11,11a-decahydro-1H-benzo[a]fluorene-9,2'-3a,4,5,6,7,7a-hexahydro-3H-furo[3,2-b]pyridine]-3-ol
Molecular formula	C₂₇H₄₁NO₂
Molecular weight	411.6 g/mol
Exact mass	411.3137
Grade	Reference Standard
HSN code	38229090
InChIKey	QASFUMOKHFSJGL-LAFRSMQTSA-N
SMILES	C[C@H]1C[C@@H]2[C@H]([C@H]([C@]3(O2)CC[C@H]4[C@@H]5CC=C6C[C@H](CC[C@@]6([C@H]5CC4=C3C)C)O)C)NC1
PubChem CID	442972

Physical properties
Physical form	Solid
LogP (XLogP3)	3.5
H-bond donors / acceptors	2 / 3
TPSA	41.5 Å²
Synonyms	11-Deoxojervine, 11-Deoxyjervine, Alkaloid V, Veratraman-3-ol, 17,23-epoxy-, (3beta,23beta)-, (3beta23R)-17,23-Epoxyveratraman-3-ol, 3,4'-Dinitroflavone, Jervine, 11-deoxo-, Cyclopamine Tartrate, EX-A952, (3beta,22S,23R)-17,23-epoxyveratraman-3-ol, Veratraman-3-ol,23-epoxy-, (3-beta,23-beta)-

Safety & hazard information (GHS)

Health hazard

Signal word: Warning

Hazard statements

H341Suspected of causing genetic defects
H361Suspected of damaging fertility or the unborn child

Precautionary statements: P203, P280, P318, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Cyclopamine?

The CAS Registry Number of Cyclopamine is 4449-51-8. It is also known as 11-Deoxojervine, 11-Deoxyjervine, Alkaloid V.

What is the molecular formula and molecular weight of Cyclopamine?

Cyclopamine has the molecular formula C27H41NO2 and a molecular weight of 411.6 g/mol.

Which grade and pack sizes of Cyclopamine can I order?

We supply Cyclopamine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Cyclopamine?

Yes. Every lot of Cyclopamine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Cyclopamine be shipped internationally?

Yes. Cyclopamine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.