Rivaroxaban Phthalimido Descarbonyl Impurity 446292-07-5

Name: Rivaroxaban Phthalimido Descarbonyl Impurity
Brand: Vaqora Chemicals
SKU: VQ-007252

About Rivaroxaban Phthalimido Descarbonyl Impurity

Vaqora Chemicals supplies Rivaroxaban Phthalimido Descarbonyl Impurity, a metabolite or degradation product of Rivaroxaban registered under CAS number 446292-07-5. Formula C21H21N3O5, molecular weight 395.4 g/mol. Systematically, it is named 2-[(2R)-2-hydroxy-3-[4-(3-oxomorpholin-4-yl)anilino]propyl]isoindole-1,3-dione. It is also known as Rivaroxaban R-Pthalamide Impurity or Rivaroxaban Impurity 94.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Analytical teams use this compound to identify metabolites and degradants of Rivaroxaban, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer Rivaroxaban Phthalimido Descarbonyl Impurity in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Rivaroxaban

View every impurity, metabolite and intermediate we list for Rivaroxaban.

Rivaroxaban impurities

Specifications & identifiers

Chemical identifiers
Product name	Rivaroxaban Phthalimido Descarbonyl Impurity
Catalogue No.	VQ-007252
CAS Number	446292-07-5
IUPAC name	2-[(2R)-2-hydroxy-3-[4-(3-oxomorpholin-4-yl)anilino]propyl]isoindole-1,3-dione
Molecular formula	C₂₁H₂₁N₃O₅
Molecular weight	395.4 g/mol
Exact mass	395.1481
Grade	Reference Standard
HSN code	38229090
InChIKey	CKFVSMPWXAASIQ-MRXNPFEDSA-N
SMILES	C1COCC(=O)N1C2=CC=C(C=C2)NC[C@H](CN3C(=O)C4=CC=CC=C4C3=O)O
PubChem CID	11516758

Physical properties
Physical form	Solid
LogP (XLogP3)	1
H-bond donors / acceptors	2 / 6
TPSA	99.2 Å²
Synonyms	Rivaroxaban R-Pthalamide Impurity, 4-[((2R)-Hydroxy-3-phthalimido)propylamine]phenyl-3-morpholinone, (R)-4-[4-(3-Phthalimido-2-hydroxy propyl amino)phenyl]-morpholin-3-one, (R)-2-(2-Hydroxy-3-((4-(3-oxomorpholino)phenyl)amino)propyl)isoindoline-1,3-dione, Rivaroxaban Impurity 94, (R)-2-(2-Hydroxy-3-((4-(3-oxomorpholino)phenyl)-amino)propyl)isoindoline-1,3-dione, (R)-2-[2-Hydroxy-3-[[4-(3-oxomorpholino)phenyl]amino]propyl]isoindoline-1,3-dione, Rivaroxaban interMediate B, Rivaroxaban Intermediates I, CS-M0561, ropyl]-1H-isoindole-1,3(2H)-dione, 2-[(2R)-2-hydroxy-3-{[4-(3-oxoMorpholin-4-yl)phenyl]aMino}p

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Rivaroxaban Phthalimido Descarbonyl Impurity?

The CAS Registry Number of Rivaroxaban Phthalimido Descarbonyl Impurity is 446292-07-5. It is also known as Rivaroxaban R-Pthalamide Impurity, 4-[((2R)-Hydroxy-3-phthalimido)propylamine]phenyl-3-morpholinone, (R)-4-[4-(3-Phthalimido-2-hydroxy propyl amino)phenyl]-morpholin-3-one.

What is the molecular formula and molecular weight of Rivaroxaban Phthalimido Descarbonyl Impurity?

Rivaroxaban Phthalimido Descarbonyl Impurity has the molecular formula C21H21N3O5 and a molecular weight of 395.4 g/mol. Its IUPAC name is 2-[(2R)-2-hydroxy-3-[4-(3-oxomorpholin-4-yl)anilino]propyl]isoindole-1,3-dione.

What is Rivaroxaban Phthalimido Descarbonyl Impurity used for?

Rivaroxaban Phthalimido Descarbonyl Impurity is supplied as a characterised reference material related to Rivaroxaban. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Rivaroxaban Phthalimido Descarbonyl Impurity can I order?

We supply Rivaroxaban Phthalimido Descarbonyl Impurity in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Rivaroxaban Phthalimido Descarbonyl Impurity?

Yes. Every lot of Rivaroxaban Phthalimido Descarbonyl Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Rivaroxaban Phthalimido Descarbonyl Impurity be shipped internationally?

Yes. Rivaroxaban Phthalimido Descarbonyl Impurity is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.