Rivaroxaban Aminomethyl Impurity

Name: Rivaroxaban Aminomethyl Impurity
Brand: Vaqora Chemicals
SKU: VQ-005785

About Rivaroxaban Aminomethyl Impurity

Rivaroxaban Aminomethyl Impurity (CAS 446292-10-0) is an impurity of Rivaroxaban offered by Vaqora Chemicals. With the molecular formula C14H17N3O4, it has a molar mass of 291.3 g/mol. Systematically, it is named 4-[4-[(5S)-5-(aminomethyl)-2-oxo-1,3-oxazolidin-3-yl]phenyl]morpholin-3-one. Alternative names: Des(5-chloro-2-carboxythienyl) Rivaroxaban and CS-M0391.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Warning” with 4 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Rivaroxaban to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Rivaroxaban Aminomethyl Impurity in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Rivaroxaban

View every impurity, metabolite and intermediate we list for Rivaroxaban.

Rivaroxaban impurities

Specifications & identifiers

Chemical identifiers
Product name	Rivaroxaban Aminomethyl Impurity
Catalogue No.	VQ-005785
CAS Number	446292-10-0
Other CAS	898543-06-1
IUPAC name	4-[4-[(5S)-5-(aminomethyl)-2-oxo-1,3-oxazolidin-3-yl]phenyl]morpholin-3-one
Molecular formula	C₁₄H₁₇N₃O₄
Molecular weight	291.3 g/mol
Exact mass	291.1219
Grade	Reference Standard
HSN code	38229090
InChIKey	DEXXSYVEWAYIGZ-LBPRGKRZSA-N
SMILES	C1COCC(=O)N1C2=CC=C(C=C2)N3C[C@@H](OC3=O)CN
PubChem CID	11346837

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.4
H-bond donors / acceptors	1 / 5
TPSA	85.1 Å²
Synonyms	Des(5-chloro-2-carboxythienyl) Rivaroxaban, (S)-4-(4-(5-(Aminomethyl)-2-oxooxazolidin-3-yl)phenyl)morpholin-3-one, 4-[4-[(5S)-5-(Aminomethyl)-2-oxo-3-oxazolidinyl]phenyl]-3-morpholinone, 4-[4-((S)-5-[Aminomethyl]-2-oxooxazolidin-3-yl)phenyl]morpholine-3-one, 4-[4-[(5S)-5-(Aminomethyl)-2-oxo-1,3-oxazolidin-3-yl]phenyl]-morpholin-3-one, (S)-4-[4-[5-(Aminomethyl)-2-oxooxazolidin-3-yl]phenyl]morpholin-3-one, 4-(4-((5S)-5-(Aminomethyl)-2-oxo-1,3-oxazolidin-3-yl)phenyl)-morpholin-3-one, 3-Morpholinone, 4-[4-[(5S)-5-(aminomethyl)-2-oxo-3-oxazolidinyl]phenyl]-, 4-{4-[(5S)-5-(Aminomethyl)-2-oxo-1,3-oxazolidin-3-yl]phenyl}morpholin-3-one, CS-M0391, 4-(4-((5S)-5-(Aminomethyl)-2-oxo-3-oxazolidinyl)phenyl)-3-morpholinone, 3-Morpholinone, 4-(4-((5S)-5-(aminomethyl)-2-oxo-3-oxazolidinyl)phenyl)-

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Rivaroxaban Aminomethyl Impurity?

The CAS Registry Number of Rivaroxaban Aminomethyl Impurity is 446292-10-0. It is also known as Des(5-chloro-2-carboxythienyl) Rivaroxaban, (S)-4-(4-(5-(Aminomethyl)-2-oxooxazolidin-3-yl)phenyl)morpholin-3-one, 4-[4-[(5S)-5-(Aminomethyl)-2-oxo-3-oxazolidinyl]phenyl]-3-morpholinone.

What is the molecular formula and molecular weight of Rivaroxaban Aminomethyl Impurity?

Rivaroxaban Aminomethyl Impurity has the molecular formula C14H17N3O4 and a molecular weight of 291.3 g/mol. Its IUPAC name is 4-[4-[(5S)-5-(aminomethyl)-2-oxo-1,3-oxazolidin-3-yl]phenyl]morpholin-3-one.

What is Rivaroxaban Aminomethyl Impurity used for?

Rivaroxaban Aminomethyl Impurity is supplied as a characterised reference material related to Rivaroxaban. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Rivaroxaban Aminomethyl Impurity can I order?

We supply Rivaroxaban Aminomethyl Impurity in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Rivaroxaban Aminomethyl Impurity?

Yes. Every lot of Rivaroxaban Aminomethyl Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Rivaroxaban Aminomethyl Impurity be shipped internationally?

Yes. Rivaroxaban Aminomethyl Impurity is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.