2,4-Difluorobenzyl Chloride
Synonyms: 2,4-Difluorobenzyl Chloride · 1-(chloromethyl)-2,4-difluoro-benzene · 2,4-difluorobenzylchloride · Benzene, 1-(chloromethyl)-2,4-difluoro-
2,4-Difluorobenzyl Chloride (CAS 452-07-3) – Relugolix intermediate. C7H5ClF2, MW 162.56. Get a quote from Vaqora Chemicals, COA included, shipped worldwide.
About 2,4-Difluorobenzyl Chloride
2,4-Difluorobenzyl Chloride is a process intermediate or related compound of Relugolix carrying the CAS registry number 452-07-3. Formula C7H5ClF2, molecular weight 162.56 g/mol. The IUPAC name is 1-(chloromethyl)-2,4-difluorobenzene. It is also known as 1-(chloromethyl)-2,4-difluoro-benzene or 2,4-difluorobenzylchloride.
It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.
It is a process intermediate or related compound in the synthesis of Relugolix, useful for route development, impurity fate-and-purge studies and analytical method development. It is used across pharmaceutical manufacturing and academic and industrial research.
Vaqora Chemicals supplies 2,4-Difluorobenzyl Chloride in 10 mg, 25 mg and 50 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. This item is currently in stock for prompt dispatch.
Typical applications
- API route development
- Impurity fate & purge studies
- Analytical method development
Industries
View every impurity, metabolite and intermediate we list for Relugolix.
Relugolix impuritiesSpecifications & identifiers
| Product name | 2,4-Difluorobenzyl Chloride |
|---|---|
| Catalogue No. | VQ-012886 |
| CAS Number | 452-07-3 |
| IUPAC name | 1-(chloromethyl)-2,4-difluorobenzene |
| Molecular formula | C7H5ClF2 |
| Molecular weight | 162.56 g/mol |
| Exact mass | 162.0048 |
| Grade | Reference Standard |
| InChIKey | XPGHWBDZNQUUQD-UHFFFAOYSA-N |
| SMILES | C1=CC(=C(C=C1F)F)CCl |
| PubChem CID | 2736948 |
| Physical form | Solid |
|---|---|
| LogP (XLogP3) | 2.8 |
| H-bond donors / acceptors | 0 / 2 |
| TPSA | 0 Ų |
| Synonyms | 2,4-Difluorobenzyl Chloride, 1-(chloromethyl)-2,4-difluoro-benzene, 2,4-difluorobenzylchloride, Benzene, 1-(chloromethyl)-2,4-difluoro-, alpha-Chloro-2,4-difluorotoluene, 2,4-difluoro-benzyl chloride |
Safety & hazard information (GHS)
Signal word: Danger
Hazard statements
H290May be corrosive to metalsH302Harmful if swallowedH314Causes severe skin burns and eye damageH318Causes serious eye damageH332Harmful if inhaled
Precautionary statements: P234, P260, P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P301 + P330 + P331, P302 + P361 + P354, P304 + P340, P305 + P354 + P338, P316, P317, P321, P330, P363, P390, P405, P406, P501
Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.
Documents
Frequently asked questions
What is the CAS number of 2,4-Difluorobenzyl Chloride?
The CAS Registry Number of 2,4-Difluorobenzyl Chloride is 452-07-3. It is also known as 2,4-Difluorobenzyl Chloride, 1-(chloromethyl)-2,4-difluoro-benzene, 2,4-difluorobenzylchloride.
What is the molecular formula and molecular weight of 2,4-Difluorobenzyl Chloride?
2,4-Difluorobenzyl Chloride has the molecular formula C7H5ClF2 and a molecular weight of 162.56 g/mol. Its IUPAC name is 1-(chloromethyl)-2,4-difluorobenzene.
What is 2,4-Difluorobenzyl Chloride used for?
2,4-Difluorobenzyl Chloride is supplied as a characterised reference material related to Relugolix. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.
Which grade and pack sizes of 2,4-Difluorobenzyl Chloride can I order?
We supply 2,4-Difluorobenzyl Chloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg packs. Larger bulk quantities and custom packing are quoted on request.
Do you provide a COA and SDS with 2,4-Difluorobenzyl Chloride?
Yes. Every lot of 2,4-Difluorobenzyl Chloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.
Can 2,4-Difluorobenzyl Chloride be shipped internationally?
Yes. 2,4-Difluorobenzyl Chloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.
Enquire about 2,4-Difluorobenzyl Chloride
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