4-(4-Methoxyphenyl)butyric acid

About 4-(4-Methoxyphenyl)butyric acid

4-(4-Methoxyphenyl)butyric acid is an impurity of Agomelatine carrying the CAS registry number 4521-28-2. Formula C11H14O3, molecular weight 194.23 g/mol. Its systematic (IUPAC) name is 4-(4-methoxyphenyl)butanoic acid. Alternative names: Benzenebutanoic acid, 4-methoxy- and 4-Methoxybenzenebutanoic acid.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Warning” with 3 hazard statements. Review the Safety Data Sheet before use.

This Agomelatine impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer 4-(4-Methoxyphenyl)butyric acid in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Agomelatine

View every impurity, metabolite and intermediate we list for Agomelatine.

Agomelatine impurities

Specifications & identifiers

Chemical identifiers
Product name	4-(4-Methoxyphenyl)butyric acid
Catalogue No.	VQ-024171
CAS Number	4521-28-2
IUPAC name	4-(4-methoxyphenyl)butanoic acid
Molecular formula	C₁₁H₁₄O₃
Molecular weight	194.23 g/mol
Exact mass	194.0943
Grade	Reference Standard
HSN code	38229090
InChIKey	LZHMNCJMXQKSBY-UHFFFAOYSA-N
SMILES	COC1=CC=C(C=C1)CCCC(=O)O
PubChem CID	78280

Physical properties
Physical form	Solid
LogP (XLogP3)	2.3
H-bond donors / acceptors	1 / 3
TPSA	46.5 Å²
Synonyms	Benzenebutanoic acid, 4-methoxy-, 4-Methoxybenzenebutanoic acid, butanoic acid, 4-(4-methoxyphenyl)-, 2-naph, 4-p-methoxyphenylbutyric acid, 4-(4-methoxyphenyl)butyric cid, 4-(p-methoxyphenyl)butyric acid, 4-(4-methoxy-phenyl)butanoic acid, 4-(4-methoxyphenyl) butanoic acid

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-(4-Methoxyphenyl)butyric acid?

The CAS Registry Number of 4-(4-Methoxyphenyl)butyric acid is 4521-28-2. It is also known as Benzenebutanoic acid, 4-methoxy-, 4-Methoxybenzenebutanoic acid, butanoic acid, 4-(4-methoxyphenyl)-.

What is the molecular formula and molecular weight of 4-(4-Methoxyphenyl)butyric acid?

4-(4-Methoxyphenyl)butyric acid has the molecular formula C11H14O3 and a molecular weight of 194.23 g/mol. Its IUPAC name is 4-(4-methoxyphenyl)butanoic acid.

What is 4-(4-Methoxyphenyl)butyric acid used for?

4-(4-Methoxyphenyl)butyric acid is supplied as a characterised reference material related to Agomelatine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-(4-Methoxyphenyl)butyric acid can I order?

We supply 4-(4-Methoxyphenyl)butyric acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-(4-Methoxyphenyl)butyric acid?

Yes. Every lot of 4-(4-Methoxyphenyl)butyric acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-(4-Methoxyphenyl)butyric acid be shipped internationally?

Yes. 4-(4-Methoxyphenyl)butyric acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.