Piperazine-1,4-diylbis(cyclopropylmethanone) 458535-34-7

Name: Piperazine-1,4-diylbis(cyclopropylmethanone)
Brand: Vaqora Chemicals
SKU: VQ-013723

About Piperazine-1,4-diylbis(cyclopropylmethanone)

Piperazine-1,4-diylbis(cyclopropylmethanone) (CAS 458535-34-7) is a process intermediate or related compound of Olaparib offered by Vaqora Chemicals. The compound has the formula C12H18N2O2, corresponding to a molecular weight of 222.28 g/mol. The IUPAC name is [4-(cyclopropanecarbonyl)piperazin-1-yl]-cyclopropylmethanone. It is also known as 1,4-bis(cyclopropylcarbonyl)-Piperazine or 1,4-Dicyclopropanecarbonylpiperazine.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Process chemists and analysts use it when developing synthetic routes to Olaparib, tracking process-related impurities and validating analytical methods. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Piperazine-1,4-diylbis(cyclopropylmethanone) in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. This item is currently in stock for prompt dispatch.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Olaparib

View every impurity, metabolite and intermediate we list for Olaparib.

Olaparib impurities

Specifications & identifiers

Chemical identifiers
Product name	Piperazine-1,4-diylbis(cyclopropylmethanone)
Catalogue No.	VQ-013723
CAS Number	458535-34-7
IUPAC name	[4-(cyclopropanecarbonyl)piperazin-1-yl]-cyclopropylmethanone
Molecular formula	C₁₂H₁₈N₂O₂
Molecular weight	222.28 g/mol
Exact mass	222.1368
Grade	Reference Standard
HSN code	2933
InChIKey	URPPSOFUADQZJE-UHFFFAOYSA-N
SMILES	C1CC1C(=O)N2CCN(CC2)C(=O)C3CC3
PubChem CID	923389

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.1
H-bond donors / acceptors	0 / 2
TPSA	40.6 Å²
Synonyms	Piperazine-1,4-diylbis(cyclopropylmethanone), 1,4-bis(cyclopropylcarbonyl)-Piperazine, 1,4-Dicyclopropanecarbonylpiperazine, (4-Cyclopropanecarbonyl-piperazin-1-yl)-cyclopropyl-methanone, Piperazine, 1,4-bis(cyclopropylcarbonyl)-

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Piperazine-1,4-diylbis(cyclopropylmethanone)?

The CAS Registry Number of Piperazine-1,4-diylbis(cyclopropylmethanone) is 458535-34-7. It is also known as Piperazine-1,4-diylbis(cyclopropylmethanone), 1,4-bis(cyclopropylcarbonyl)-Piperazine, 1,4-Dicyclopropanecarbonylpiperazine.

What is the molecular formula and molecular weight of Piperazine-1,4-diylbis(cyclopropylmethanone)?

Piperazine-1,4-diylbis(cyclopropylmethanone) has the molecular formula C12H18N2O2 and a molecular weight of 222.28 g/mol. Its IUPAC name is [4-(cyclopropanecarbonyl)piperazin-1-yl]-cyclopropylmethanone.

What is Piperazine-1,4-diylbis(cyclopropylmethanone) used for?

Piperazine-1,4-diylbis(cyclopropylmethanone) is supplied as a characterised reference material related to Olaparib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Piperazine-1,4-diylbis(cyclopropylmethanone) can I order?

We supply Piperazine-1,4-diylbis(cyclopropylmethanone) in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Piperazine-1,4-diylbis(cyclopropylmethanone)?

Yes. Every lot of Piperazine-1,4-diylbis(cyclopropylmethanone) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Piperazine-1,4-diylbis(cyclopropylmethanone) be shipped internationally?

Yes. We export Piperazine-1,4-diylbis(cyclopropylmethanone) worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.