Alvespimycin Hydrochloride

About Alvespimycin Hydrochloride

Alvespimycin Hydrochloride is an impurity of Geldanamycin carrying the CAS registry number 467214-21-7. Formula C32H49ClN4O8, molecular weight 653.2 g/mol. It is also known as Alvespimycin HCl or 17-DMAG HCl.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

This Geldanamycin impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Alvespimycin Hydrochloride is dispatched with a Certificate of Analysis (COA) to destinations worldwide. A Safety Data Sheet (SDS) and technical specifications are available on request.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Geldanamycin

View every impurity, metabolite and intermediate we list for Geldanamycin.

Geldanamycin impurities

Specifications & identifiers

Chemical identifiers
Product name	Alvespimycin Hydrochloride
Catalogue No.	VQ-044526
CAS Number	467214-21-7
IUPAC name	[(4E,6Z,8S,9S,10E,12S,13R,14S,16R)-19-[2-(dimethylamino)ethylamino]-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl] carbamate;hydrochloride
Molecular formula	C₃₂H₄₉ClN₄O₈
Molecular weight	653.2 g/mol
Exact mass	652.3239
Grade	Reference Standard
HSN code	38229090
InChIKey	DFSYBWLNYPEFJK-IHLRWNDRSA-N
SMILES	C[C@H]1C[C@@H]([C@@H]([C@H](/C=C(/[C@@H]([C@H](/C=C\C=C(\C(=O)NC2=CC(=O)C(=C(C1)C2=O)NCCN(C)C)/C)OC)OC(=O)N)\C)C)O)OC.Cl
PubChem CID	9852573

Physical properties
Physical form	Solid
H-bond donors / acceptors	5 / 10
TPSA	170 Å²
Synonyms	Alvespimycin HCl, 17-DMAG HCl, KOS-1022, Alvespimycin hydrochloride (USAN), Geldanamycin,17-demethoxy-17-((2-(dimethylamino)ethyl)amino)-, monohydrochloride, 17-DMAG (Alvespimycin) HCl, 17-DMAG hydrochloride, Alvespimycin (17-DMAG) HCl, 17-DMAG.HCl, EX-A4128

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Alvespimycin Hydrochloride?

The CAS Registry Number of Alvespimycin Hydrochloride is 467214-21-7. It is also known as Alvespimycin HCl, 17-DMAG HCl, KOS-1022.

What is the molecular formula and molecular weight of Alvespimycin Hydrochloride?

Alvespimycin Hydrochloride has the molecular formula C32H49ClN4O8 and a molecular weight of 653.2 g/mol.

What is Alvespimycin Hydrochloride used for?

Alvespimycin Hydrochloride is supplied as a characterised reference material related to Geldanamycin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Alvespimycin Hydrochloride can I order?

We supply Alvespimycin Hydrochloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Alvespimycin Hydrochloride?

Yes. Every lot of Alvespimycin Hydrochloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Alvespimycin Hydrochloride be shipped internationally?

Yes. We export Alvespimycin Hydrochloride worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.