Hamamelitannin

About Hamamelitannin

Hamamelitannin is an impurity of Melatonin carrying the CAS registry number 469-32-9. Its molecular formula is C20H20O14 and its molecular weight is 484.4 g/mol. Systematically, it is named [(2R,3R,4R)-4-formyl-2,3,4-trihydroxy-5-(3,4,5-trihydroxybenzoyl)oxypentyl] 3,4,5-trihydroxybenzoate. Alternative names: 2',5-Di-O-galloyl hamamelose and digalloylhamamelose.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

This Melatonin impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Melatonin

View every impurity, metabolite and intermediate we list for Melatonin.

Melatonin impurities

Specifications & identifiers

Chemical identifiers
Product name	Hamamelitannin
Catalogue No.	VQ-039981
CAS Number	469-32-9
IUPAC name	[(2R,3R,4R)-4-formyl-2,3,4-trihydroxy-5-(3,4,5-trihydroxybenzoyl)oxypentyl] 3,4,5-trihydroxybenzoate
Molecular formula	C₂₀H₂₀O₁₄
Molecular weight	484.4 g/mol
Exact mass	484.0853
Grade	Reference Standard
HSN code	38229090
InChIKey	STINYPFJROKCKD-WIBUTAKZSA-N
SMILES	C1=C(C=C(C(=C1O)O)O)C(=O)OC[C@H]([C@H]([C@](COC(=O)C2=CC(=C(C(=C2)O)O)O)(C=O)O)O)O
PubChem CID	21145076

Physical properties
Physical form	Solid
LogP (XLogP3)	-1.3
H-bond donors / acceptors	9 / 14
TPSA	252 Å²
Synonyms	2',5-Di-O-galloyl hamamelose, D-Ribofuranose, 2-C-(((3,4,5-trihydroxybenzoyl)oxy)methyl)-, 5-(3,4,5-trihydroxybenzoate), digalloylhamamelose, hamamelitannin (open form), 2-C-((Galloyloxy)methyl)-D-ribose 5-gallate, Gallic acid, 21,5-diester with 2-C-(hydroxymethyl)-D-ribose

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Hamamelitannin?

The CAS Registry Number of Hamamelitannin is 469-32-9. It is also known as 2',5-Di-O-galloyl hamamelose, D-Ribofuranose, 2-C-(((3,4,5-trihydroxybenzoyl)oxy)methyl)-, 5-(3,4,5-trihydroxybenzoate), digalloylhamamelose.

What is the molecular formula and molecular weight of Hamamelitannin?

Hamamelitannin has the molecular formula C20H20O14 and a molecular weight of 484.4 g/mol. Its IUPAC name is [(2R,3R,4R)-4-formyl-2,3,4-trihydroxy-5-(3,4,5-trihydroxybenzoyl)oxypentyl] 3,4,5-trihydroxybenzoate.

What is Hamamelitannin used for?

Hamamelitannin is supplied as a characterised reference material related to Melatonin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Hamamelitannin can I order?

We supply Hamamelitannin in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Hamamelitannin?

Yes. Every lot of Hamamelitannin is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Hamamelitannin be shipped internationally?

Yes. We export Hamamelitannin worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.