Seneciphylline

Name: Seneciphylline
Brand: Vaqora Chemicals
SKU: VQ-033810

About Seneciphylline

Vaqora Chemicals supplies Seneciphylline, a high-purity reference standard of Seneciphylline registered under CAS number 480-81-9. With the molecular formula C18H23NO5, it has a molar mass of 333.4 g/mol. Common synonyms include Seneciphyllin and Jacodine.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

As a reference sample of Seneciphylline, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Seneciphylline in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Seneciphylline

View every impurity, metabolite and intermediate we list for Seneciphylline.

Seneciphylline impurities

Specifications & identifiers

Chemical identifiers
Product name	Seneciphylline
Catalogue No.	VQ-033810
CAS Number	480-81-9
IUPAC name	(1R,4Z,7R,17R)-4-ethylidene-7-hydroxy-7-methyl-6-methylidene-2,9-dioxa-14-azatricyclo[9.5.1.014,17]heptadec-11-ene-3,8-dione
Molecular formula	C₁₈H₂₃NO₅
Molecular weight	333.4 g/mol
Exact mass	333.1576
Grade	Reference Standard
HSN code	38229090
InChIKey	FCEVNJIUIMLVML-QPSVUOIXSA-N
SMILES	C/C=C\1/CC(=C)[C@@](C(=O)OCC2=CCN3[C@H]2[C@@H](CC3)OC1=O)(C)O
PubChem CID	5281750

Physical properties
Physical form	Solid
LogP (XLogP3)	0.7
H-bond donors / acceptors	1 / 6
TPSA	76.1 Å²
Synonyms	Seneciphyllin, Jacodine, 13,19-Didehydro-12-hydroxysenecionan-11,16-dione, Senecionan-11,16-dione, 13,19-didehydro-12-hydroxy-, trans-15-Ethylidene-12beta-hydroxy-12alpha-methyl-13-methylenesenec-1-enine, Seniciphylline, senenciphylline, Seneciophylline, Senecionan-11, 13,19-didehydro-12-hydroxy-, (15Z)-12-Hydroxy-13,19-didehydrosenecionan-11,16-dione

Safety & hazard information (GHS)

Toxic

Signal word: Danger

Hazard statements

H301Toxic if swallowed

Precautionary statements: P264, P270, P301 + P316, P321, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Seneciphylline?

The CAS Registry Number of Seneciphylline is 480-81-9. It is also known as Seneciphyllin, Jacodine, 13,19-Didehydro-12-hydroxysenecionan-11,16-dione.

What is the molecular formula and molecular weight of Seneciphylline?

Seneciphylline has the molecular formula C18H23NO5 and a molecular weight of 333.4 g/mol. Its IUPAC name is (1R,4Z,7R,17R)-4-ethylidene-7-hydroxy-7-methyl-6-methylidene-2,9-dioxa-14-azatricyclo[9.5.1.014,17]heptadec-11-ene-3,8-dione.

What is Seneciphylline used for?

Seneciphylline is supplied as a characterised reference material related to Seneciphylline. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Seneciphylline can I order?

We supply Seneciphylline in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Seneciphylline?

Yes. Every lot of Seneciphylline is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Seneciphylline be shipped internationally?

Yes. Seneciphylline is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.