(1R,2S,5S)-tert-Butyl Edoxaban

About (1R,2S,5S)-tert-Butyl Edoxaban

(1R,2S,5S)-tert-Butyl Edoxaban is an impurity of Edoxaban carrying the CAS registry number 480452-36-6. The compound has the formula C21H30ClN5O5, corresponding to a molecular weight of 467.9 g/mol. Common synonyms include Edoxaban-4.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

As a characterised impurity of Edoxaban, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer (1R,2S,5S)-tert-Butyl Edoxaban in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Edoxaban

View every impurity, metabolite and intermediate we list for Edoxaban.

Edoxaban impurities

Specifications & identifiers

Chemical identifiers
Product name	(1R,2S,5S)-tert-Butyl Edoxaban
Catalogue No.	VQ-022487
CAS Number	480452-36-6
IUPAC name	tert-butyl N-[(1R,2S,5S)-2-[[2-[(5-chloro-2-pyridinyl)amino]-2-oxoacetyl]amino]-5-(dimethylcarbamoyl)cyclohexyl]carbamate
Molecular formula	C₂₁H₃₀ClN₅O₅
Molecular weight	467.9 g/mol
Exact mass	467.1935
Grade	Reference Standard
HSN code	38229090
InChIKey	YJDLJNAWLBVIRF-AEGPPILISA-N
SMILES	CC(C)(C)OC(=O)N[C@@H]1C[C@H](CC[C@@H]1NC(=O)C(=O)NC2=NC=C(C=C2)Cl)C(=O)N(C)C
PubChem CID	46911214

Physical properties
Physical form	Solid
LogP (XLogP3)	1.8
H-bond donors / acceptors	3 / 6
TPSA	130 Å²

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H412Harmful to aquatic life with long lasting effects

Precautionary statements: P261, P264, P264 + P265, P270, P271, P273, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (1R,2S,5S)-tert-Butyl Edoxaban?

The CAS Registry Number of (1R,2S,5S)-tert-Butyl Edoxaban is 480452-36-6. It is also known as Edoxaban-4.

What is the molecular formula and molecular weight of (1R,2S,5S)-tert-Butyl Edoxaban?

(1R,2S,5S)-tert-Butyl Edoxaban has the molecular formula C21H30ClN5O5 and a molecular weight of 467.9 g/mol. Its IUPAC name is tert-butyl N-[(1R,2S,5S)-2-[[2-[(5-chloro-2-pyridinyl)amino]-2-oxoacetyl]amino]-5-(dimethylcarbamoyl)cyclohexyl]carbamate.

What is (1R,2S,5S)-tert-Butyl Edoxaban used for?

(1R,2S,5S)-tert-Butyl Edoxaban is supplied as a characterised reference material related to Edoxaban. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (1R,2S,5S)-tert-Butyl Edoxaban can I order?

We supply (1R,2S,5S)-tert-Butyl Edoxaban in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (1R,2S,5S)-tert-Butyl Edoxaban?

Yes. Every lot of (1R,2S,5S)-tert-Butyl Edoxaban is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (1R,2S,5S)-tert-Butyl Edoxaban be shipped internationally?

Yes. (1R,2S,5S)-tert-Butyl Edoxaban is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.