N1-((1S, 2R,4S)-2-Amino-4-(dimethylcarbamoyl)… 480452-37-7

About N1-((1S, 2R,4S)-2-Amino-4-(dimethylcarbamoyl)cyclohexyl)- N2-(5-chloro pyridin-2-yl)oxalamide

N1-((1S, 2R,4S)-2-Amino-4-(dimethylcarbamoyl)cyclohexyl)- N2-(5-chloro pyridin-2-yl)oxalamide is an impurity of Edoxaban carrying the CAS registry number 480452-37-7. Its molecular formula is C16H22ClN5O3 and its molecular weight is 367.8 g/mol. Systematically, it is named N-[(1S,2R,4S)-2-amino-4-(dimethylcarbamoyl)cyclohexyl]-N'-(5-chloro-2-pyridinyl)oxamide. Common synonyms include Edoxaban-6.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Edoxaban to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, N1-((1S, 2R,4S)-2-Amino-4-(dimethylcarbamoyl)cyclohexyl)- N2-(5-chloro pyridin-2-yl)oxalamide is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Edoxaban

View every impurity, metabolite and intermediate we list for Edoxaban.

Edoxaban impurities

Specifications & identifiers

Chemical identifiers
Product name	N1-((1S, 2R,4S)-2-Amino-4-(dimethylcarbamoyl)cyclohexyl)- N2-(5-chloro pyridin-2-yl)oxalamide
Catalogue No.	VQ-030375
CAS Number	480452-37-7
IUPAC name	N-[(1S,2R,4S)-2-amino-4-(dimethylcarbamoyl)cyclohexyl]-N'-(5-chloro-2-pyridinyl)oxamide
Molecular formula	C₁₆H₂₂ClN₅O₃
Molecular weight	367.8 g/mol
Exact mass	367.1411
Grade	Reference Standard
HSN code	38229090
InChIKey	IZABLUDXAWYTNU-WCQGTBRESA-N
SMILES	CN(C)C(=O)[C@H]1CC[C@@H]([C@@H](C1)N)NC(=O)C(=O)NC2=NC=C(C=C2)Cl
PubChem CID	59676986

Physical properties
Physical form	Solid
LogP (XLogP3)	0.2
H-bond donors / acceptors	3 / 5
TPSA	117 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N1-((1S, 2R,4S)-2-Amino-4-(dimethylcarbamoyl)cyclohexyl)- N2-(5-chloro pyridin-2-yl)oxalamide?

The CAS Registry Number of N1-((1S, 2R,4S)-2-Amino-4-(dimethylcarbamoyl)cyclohexyl)- N2-(5-chloro pyridin-2-yl)oxalamide is 480452-37-7. It is also known as Edoxaban-6, N-[(1S,2R,4S)-2-amino-4-(dimethylcarbamoyl)cyclohexyl]-N'-(5-chloropyridin-2-yl)oxamide, N-[(1S,2R,4S)-2-amino-4-(dimethylcarbamoyl)cyclohexyl]-N'-(5-chloro-2-pyridyl)oxamide.

What is the molecular formula and molecular weight of N1-((1S, 2R,4S)-2-Amino-4-(dimethylcarbamoyl)cyclohexyl)- N2-(5-chloro pyridin-2-yl)oxalamide?

N1-((1S, 2R,4S)-2-Amino-4-(dimethylcarbamoyl)cyclohexyl)- N2-(5-chloro pyridin-2-yl)oxalamide has the molecular formula C16H22ClN5O3 and a molecular weight of 367.8 g/mol. Its IUPAC name is N-[(1S,2R,4S)-2-amino-4-(dimethylcarbamoyl)cyclohexyl]-N'-(5-chloro-2-pyridinyl)oxamide.

What is N1-((1S, 2R,4S)-2-Amino-4-(dimethylcarbamoyl)cyclohexyl)- N2-(5-chloro pyridin-2-yl)oxalamide used for?

N1-((1S, 2R,4S)-2-Amino-4-(dimethylcarbamoyl)cyclohexyl)- N2-(5-chloro pyridin-2-yl)oxalamide is supplied as a characterised reference material related to Edoxaban. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N1-((1S, 2R,4S)-2-Amino-4-(dimethylcarbamoyl)cyclohexyl)- N2-(5-chloro pyridin-2-yl)oxalamide can I order?

We supply N1-((1S, 2R,4S)-2-Amino-4-(dimethylcarbamoyl)cyclohexyl)- N2-(5-chloro pyridin-2-yl)oxalamide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N1-((1S, 2R,4S)-2-Amino-4-(dimethylcarbamoyl)cyclohexyl)- N2-(5-chloro pyridin-2-yl)oxalamide?

Yes. Every lot of N1-((1S, 2R,4S)-2-Amino-4-(dimethylcarbamoyl)cyclohexyl)- N2-(5-chloro pyridin-2-yl)oxalamide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N1-((1S, 2R,4S)-2-Amino-4-(dimethylcarbamoyl)cyclohexyl)- N2-(5-chloro pyridin-2-yl)oxalamide be shipped internationally?

Yes. We export N1-((1S, 2R,4S)-2-Amino-4-(dimethylcarbamoyl)cyclohexyl)- N2-(5-chloro pyridin-2-yl)oxalamide worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.