Cinchonidine

Name: Cinchonidine
Brand: Vaqora Chemicals
SKU: VQ-024987

About Cinchonidine

Cinchonidine is an impurity of Quinine carrying the CAS registry number 485-71-2. The compound has the formula C19H22N2O, corresponding to a molecular weight of 294.4 g/mol. Systematically, it is named (R)-[(2S,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-quinolin-4-ylmethanol. Alternative names: Cinchovatine and (8S,9R)-Cinchonidine.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

This Quinine impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Cinchonidine in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Quinine

View every impurity, metabolite and intermediate we list for Quinine.

Quinine impurities

Specifications & identifiers

Chemical identifiers
Product name	Cinchonidine
Catalogue No.	VQ-024987
CAS Number	485-71-2
IUPAC name	(R)-[(2S,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-quinolin-4-ylmethanol
Molecular formula	C₁₉H₂₂N₂O
Molecular weight	294.4 g/mol
Exact mass	294.1732
Grade	Reference Standard
HSN code	38229090
InChIKey	KMPWYEUPVWOPIM-KODHJQJWSA-N
SMILES	C=C[C@H]1CN2CC[C@H]1C[C@H]2[C@@H](C3=CC=NC4=CC=CC=C34)O
PubChem CID	101744

Physical properties
Physical form	Solid
LogP (XLogP3)	2.7
H-bond donors / acceptors	1 / 3
TPSA	36.4 Å²
Synonyms	Cinchovatine, (8S,9R)-Cinchonidine, Cinchovatine-, (8-alpha,9R)-Cinchonan-9-ol, (8alpha,9R)-Cinchonan-9-ol, Cinchonan-9-ol, (8alpha,9R)-, 2-Quinuclidinemethanol, alpha-4-quinolyl-5-vinyl-, (R)-((2S,4S,5R)-5-ethenyl-1-azabicyclo(2.2.2)octan-2-yl)-quinolin-4-ylmethanol, L-Cinchonidine, (8S,9R)-cinchonan-9-ol, (R)-quinolin-4-yl((1S,2S,4S,5R)-5-vinylquinuclidin-2-yl)methanol

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H317May cause an allergic skin reaction
H361Suspected of damaging fertility or the unborn child
H373May causes damage to organs through prolonged or repeated exposure

Precautionary statements: P203, P260, P261, P264, P270, P272, P280, P301 + P317, P302 + P352, P318, P319, P321, P330, P333 + P317, P362 + P364, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Cinchonidine?

The CAS Registry Number of Cinchonidine is 485-71-2. It is also known as Cinchovatine, (8S,9R)-Cinchonidine, Cinchovatine-.

What is the molecular formula and molecular weight of Cinchonidine?

Cinchonidine has the molecular formula C19H22N2O and a molecular weight of 294.4 g/mol. Its IUPAC name is (R)-[(2S,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-quinolin-4-ylmethanol.

What is Cinchonidine used for?

Cinchonidine is supplied as a characterised reference material related to Quinine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Cinchonidine can I order?

We supply Cinchonidine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Cinchonidine?

Yes. Every lot of Cinchonidine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Cinchonidine be shipped internationally?

Yes. Cinchonidine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.