2-Phenylpropionic acid

About 2-Phenylpropionic acid

2-Phenylpropionic acid is a process intermediate or related compound of Loxoprofen carrying the CAS registry number 492-37-5. Formula C9H10O2, molecular weight 150.17 g/mol. The IUPAC name is 2-phenylpropanoic acid. Common synonyms include Hydratropic Acid and alpha-Methylphenylacetic acid.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Process chemists and analysts use it when developing synthetic routes to Loxoprofen, tracking process-related impurities and validating analytical methods. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development
Fine chemical synthesis

Industries

Related to Loxoprofen

View every impurity, metabolite and intermediate we list for Loxoprofen.

Loxoprofen impurities

Specifications & identifiers

Chemical identifiers
Product name	2-Phenylpropionic acid
Catalogue No.	VQ-037628
CAS Number	492-37-5
IUPAC name	2-phenylpropanoic acid
Molecular formula	C₉H₁₀O₂
Molecular weight	150.17 g/mol
Exact mass	150.0681
InChIKey	YPGCWEMNNLXISK-UHFFFAOYSA-N
SMILES	CC(C1=CC=CC=C1)C(=O)O
PubChem CID	10296

Physical properties
Physical form	Solid
LogP (XLogP3)	1.9
H-bond donors / acceptors	1 / 2
TPSA	37.3 Å²
Synonyms	Hydratropic Acid, alpha-Methylphenylacetic acid, alpha-Methylbenzeneacetic acid, alpha-methyl-benzeneacetic acid /OD/ 2-phenylpropionic acid, DL-2-Phenylpropionic Acid, (+/-)-2-phenylpropanoic acid, Benzeneacetic acid, .alpha.-methyl-, (+/-)-Hydratropic acid, .alpha.-Methylphenylacetic acid, .alpha.-Methylbenzeneacetic acid, (+-)-Hydratropasaeure

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2-Phenylpropionic acid?

The CAS Registry Number of 2-Phenylpropionic acid is 492-37-5. It is also known as Hydratropic Acid, alpha-Methylphenylacetic acid, alpha-Methylbenzeneacetic acid.

What is the molecular formula and molecular weight of 2-Phenylpropionic acid?

2-Phenylpropionic acid has the molecular formula C9H10O2 and a molecular weight of 150.17 g/mol. Its IUPAC name is 2-phenylpropanoic acid.

What is 2-Phenylpropionic acid used for?

2-Phenylpropionic acid is supplied as a characterised reference material related to Loxoprofen. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2-Phenylpropionic acid can I order?

We supply 2-Phenylpropionic acid, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-Phenylpropionic acid?

Yes. Every lot of 2-Phenylpropionic acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-Phenylpropionic acid be shipped internationally?

Yes. 2-Phenylpropionic acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.