Ethyl 6-Chloronicotinate

Name: Ethyl 6-Chloronicotinate
Brand: Vaqora Chemicals
SKU: VQ-034066

About Ethyl 6-Chloronicotinate

Vaqora Chemicals supplies Ethyl 6-Chloronicotinate, an impurity of Tazarotene registered under CAS number 49608-01-7. Its molecular formula is C8H8ClNO2 and its molecular weight is 185.61 g/mol. Its systematic (IUPAC) name is ethyl 6-chloropyridine-3-carboxylate. It is also known as 6-Chloronicotinic Acid Ethyl Ester or Ethyl 6-chloro-3-pyridinecarboxylate.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

This Tazarotene impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Ethyl 6-Chloronicotinate in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Tazarotene

View every impurity, metabolite and intermediate we list for Tazarotene.

Tazarotene impurities

Specifications & identifiers

Chemical identifiers
Product name	Ethyl 6-Chloronicotinate
Catalogue No.	VQ-034066
CAS Number	49608-01-7
IUPAC name	ethyl 6-chloropyridine-3-carboxylate
Molecular formula	C₈H₈ClNO₂
Molecular weight	185.61 g/mol
Exact mass	185.0244
Grade	Reference Standard
HSN code	38229090
InChIKey	ILDJJTQWIZLGPO-UHFFFAOYSA-N
SMILES	CCOC(=O)C1=CN=C(C=C1)Cl
PubChem CID	2799611

Physical properties
Physical form	Solid
LogP (XLogP3)	2.3
H-bond donors / acceptors	0 / 3
TPSA	39.2 Å²
Synonyms	6-Chloronicotinic Acid Ethyl Ester, Ethyl 6-chloro-3-pyridinecarboxylate, 6-chloro-nicotinic acid ethyl ester, ethyl 2-chloro-5-pyridinecarboxylate, 6-chloro nicotinic acid ethyl ester, Ethyl 6-chloronicotinoate, 2-Chloro-5-pyridinecarboxylic Acid Ethyl Ester

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ethyl 6-Chloronicotinate?

The CAS Registry Number of Ethyl 6-Chloronicotinate is 49608-01-7. It is also known as 6-Chloronicotinic Acid Ethyl Ester, Ethyl 6-chloro-3-pyridinecarboxylate, 6-chloro-nicotinic acid ethyl ester.

What is the molecular formula and molecular weight of Ethyl 6-Chloronicotinate?

Ethyl 6-Chloronicotinate has the molecular formula C8H8ClNO2 and a molecular weight of 185.61 g/mol. Its IUPAC name is ethyl 6-chloropyridine-3-carboxylate.

What is Ethyl 6-Chloronicotinate used for?

Ethyl 6-Chloronicotinate is supplied as a characterised reference material related to Tazarotene. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ethyl 6-Chloronicotinate can I order?

We supply Ethyl 6-Chloronicotinate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ethyl 6-Chloronicotinate?

Yes. Every lot of Ethyl 6-Chloronicotinate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ethyl 6-Chloronicotinate be shipped internationally?

Yes. Ethyl 6-Chloronicotinate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.