4-(Difluoromethyl)aniline

About 4-(Difluoromethyl)aniline

4-(Difluoromethyl)aniline is a process intermediate or related compound of Teriflunomide carrying the CAS registry number 49658-26-6. With the molecular formula C7H7F2N, it has a molar mass of 143.13 g/mol. Common synonyms include 4-(Difluoromethyl)benzenamine and p-(Difluoromethyl)aniline.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

Process chemists and analysts use it when developing synthetic routes to Teriflunomide, tracking process-related impurities and validating analytical methods. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer 4-(Difluoromethyl)aniline in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. Stock is available for quick dispatch.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Teriflunomide

View every impurity, metabolite and intermediate we list for Teriflunomide.

Teriflunomide impurities

Specifications & identifiers

Chemical identifiers
Product name	4-(Difluoromethyl)aniline
Catalogue No.	VQ-013069
CAS Number	49658-26-6
Other CAS	1980063-54-4
IUPAC name	4-(difluoromethyl)aniline
Molecular formula	C₇H₇F₂N
Molecular weight	143.13 g/mol
Exact mass	143.0547
Grade	Reference Standard
HSN code	2933
InChIKey	FRVATKJLVXRQHU-UHFFFAOYSA-N
SMILES	C1=CC(=CC=C1C(F)F)N
PubChem CID	53435198

Physical properties
Physical form	Solid
LogP (XLogP3)	1.6
H-bond donors / acceptors	1 / 3
TPSA	26 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-(Difluoromethyl)aniline?

The CAS Registry Number of 4-(Difluoromethyl)aniline is 49658-26-6. It is also known as 4-(Difluoromethyl)benzenamine, p-(Difluoromethyl)aniline, alpha, alpha-Difluoro-p-toluidine.

What is the molecular formula and molecular weight of 4-(Difluoromethyl)aniline?

4-(Difluoromethyl)aniline has the molecular formula C7H7F2N and a molecular weight of 143.13 g/mol. Its IUPAC name is 4-(difluoromethyl)aniline.

What is 4-(Difluoromethyl)aniline used for?

4-(Difluoromethyl)aniline is supplied as a characterised reference material related to Teriflunomide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-(Difluoromethyl)aniline can I order?

We supply 4-(Difluoromethyl)aniline in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-(Difluoromethyl)aniline?

Yes. Every lot of 4-(Difluoromethyl)aniline is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-(Difluoromethyl)aniline be shipped internationally?

Yes. We export 4-(Difluoromethyl)aniline worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.