Lurbinectedin

About Lurbinectedin

Lurbinectedin is a high-purity reference standard of Lurbinectedin carrying the CAS registry number 497871-47-3. Its molecular formula is C41H44N4O10S and its molecular weight is 784.9 g/mol. Common synonyms include Tryptamicidin and lurbinectedine.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Laboratories use this Lurbinectedin standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer Lurbinectedin in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Lurbinectedin

View every impurity, metabolite and intermediate we list for Lurbinectedin.

Lurbinectedin impurities

Specifications & identifiers

Chemical identifiers
Product name	Lurbinectedin
Catalogue No.	VQ-038218
CAS Number	497871-47-3
IUPAC name	[(1R,2R,3R,11S,12S,14R,26R)-5,12-dihydroxy-6,6'-dimethoxy-7,21,30-trimethyl-27-oxospiro[17,19,28-trioxa-24-thia-13,30-diazaheptacyclo[12.9.6.13,11.02,13.04,9.015,23.016,20]triaconta-4(9),5,7,15,20,22-hexaene-26,1'-2,3,4,9-tetrahydropyrido[3,4-b]indole]-22-yl] acetate
Molecular formula	C₄₁H₄₄N₄O₁₀S
Molecular weight	784.9 g/mol
Exact mass	784.2778
Grade	Reference Standard
HSN code	38229090
InChIKey	YDDMIZRDDREKEP-HWTBNCOESA-N
SMILES	CC1=CC2=C([C@@H]3[C@@H]4[C@H]5C6=C(C(=C7C(=C6[C@@H](N4[C@H]([C@H](C2)N3C)O)COC(=O)[C@@]8(CS5)C9=C(CCN8)C2=C(N9)C=CC(=C2)OC)OCO7)C)OC(=O)C)C(=C1OC)O
PubChem CID	57327016

Physical properties
Physical form	Solid
LogP (XLogP3)	3.9
H-bond donors / acceptors	4 / 14
TPSA	190 Å²
Synonyms	Tryptamicidin, lurbinectedine, Lurbinectedin (PM01183), EX-A4316, WHO 9397

Safety & hazard information (GHS)

Harmful / irritant

Environmental hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects

Precautionary statements: P264, P270, P273, P301 + P317, P330, P391, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Lurbinectedin?

The CAS Registry Number of Lurbinectedin is 497871-47-3. It is also known as Tryptamicidin, lurbinectedine, Lurbinectedin (PM01183).

What is the molecular formula and molecular weight of Lurbinectedin?

Lurbinectedin has the molecular formula C41H44N4O10S and a molecular weight of 784.9 g/mol.

What is Lurbinectedin used for?

Lurbinectedin is supplied as a characterised reference material related to Lurbinectedin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Lurbinectedin can I order?

We supply Lurbinectedin in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Lurbinectedin?

Yes. Every lot of Lurbinectedin is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Lurbinectedin be shipped internationally?

Yes. Lurbinectedin is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.