2-Hydroxy Ethynyl Estradiol

Name: 2-Hydroxy Ethynyl Estradiol
Brand: Vaqora Chemicals
SKU: VQ-037128

About 2-Hydroxy Ethynyl Estradiol

2-Hydroxy Ethynyl Estradiol (CAS 50394-89-3) is a metabolite or degradation product of Ethinylestradiol offered by Vaqora Chemicals. With the molecular formula C20H24O3, it has a molar mass of 312.4 g/mol. Common synonyms include 2-Hydroxy Ethinylestradiol and 2-hydroxyethinylestradiol.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

Analytical teams use this compound to identify metabolites and degradants of Ethinylestradiol, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 2-Hydroxy Ethynyl Estradiol in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Ethinylestradiol

View every impurity, metabolite and intermediate we list for Ethinylestradiol.

Ethinylestradiol impurities

Specifications & identifiers

Chemical identifiers
Product name	2-Hydroxy Ethynyl Estradiol
Catalogue No.	VQ-037128
CAS Number	50394-89-3
IUPAC name	(8R,9S,13S,14S,17R)-17-ethynyl-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-2,3,17-triol
Molecular formula	C₂₀H₂₄O₃
Molecular weight	312.4 g/mol
Exact mass	312.1725
Grade	Reference Standard
HSN code	38229090
InChIKey	KQJCDKMHNQVWDV-BKRJIHRRSA-N
SMILES	C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@]2(C#C)O)CCC4=CC(=C(C=C34)O)O
PubChem CID	40561832

Physical properties
Physical form	Solid
LogP (XLogP3)	3.3
H-bond donors / acceptors	3 / 3
TPSA	60.7 Å²
Synonyms	2-Hydroxy Ethinylestradiol, 19-norpregna-1,3,5(10)-trien-20-yne-2,3,17 alpha-triol, 2-hydroxyethinylestradiol, 17a-Ethynyl-2-hydroxyestradiol, 17alpha-ethinyl-estra-1,3,5(10)-triene-2,3,17beta-triol, 19-Norpregna-1,3,5(10)-trien-20-yne-2,3,17alpha-triol, (17a)-19-Norpregna-1,3,5(10)-trien-20-yne-2,3,17-triol

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2-Hydroxy Ethynyl Estradiol?

The CAS Registry Number of 2-Hydroxy Ethynyl Estradiol is 50394-89-3. It is also known as 2-Hydroxy Ethinylestradiol, 19-norpregna-1,3,5(10)-trien-20-yne-2,3,17 alpha-triol, 2-hydroxyethinylestradiol.

What is the molecular formula and molecular weight of 2-Hydroxy Ethynyl Estradiol?

2-Hydroxy Ethynyl Estradiol has the molecular formula C20H24O3 and a molecular weight of 312.4 g/mol. Its IUPAC name is (8R,9S,13S,14S,17R)-17-ethynyl-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-2,3,17-triol.

What is 2-Hydroxy Ethynyl Estradiol used for?

2-Hydroxy Ethynyl Estradiol is supplied as a characterised reference material related to Ethinylestradiol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2-Hydroxy Ethynyl Estradiol can I order?

We supply 2-Hydroxy Ethynyl Estradiol in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-Hydroxy Ethynyl Estradiol?

Yes. Every lot of 2-Hydroxy Ethynyl Estradiol is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-Hydroxy Ethynyl Estradiol be shipped internationally?

Yes. We export 2-Hydroxy Ethynyl Estradiol worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.