Vortioxetine

About Vortioxetine

Vortioxetine is a high-purity reference standard of Vortioxetine carrying the CAS registry number 508233-74-7. The compound has the formula C18H22N2S, corresponding to a molecular weight of 298.4 g/mol. The IUPAC name is 1-[2-(2,4-dimethylphenyl)sulfanylphenyl]piperazine. Common synonyms include Brintellix and Trintellix.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 6 hazard statements. Review the Safety Data Sheet before use.

Laboratories use this Vortioxetine standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer Vortioxetine in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Vortioxetine

View every impurity, metabolite and intermediate we list for Vortioxetine.

Vortioxetine impurities

Specifications & identifiers

Chemical identifiers
Product name	Vortioxetine
Catalogue No.	VQ-007855
CAS Number	508233-74-7
Other CAS	960203-27-4, 960203-28-5, 1793058-29-3
IUPAC name	1-[2-(2,4-dimethylphenyl)sulfanylphenyl]piperazine
Molecular formula	C₁₈H₂₂N₂S
Molecular weight	298.4 g/mol
Exact mass	298.1504
Grade	Reference Standard
HSN code	38229090
InChIKey	YQNWZWMKLDQSAC-UHFFFAOYSA-N
SMILES	CC1=CC(=C(C=C1)SC2=CC=CC=C2N3CCNCC3)C
PubChem CID	9966051

Physical properties
Physical form	Solid
LogP (XLogP3)	4.2
H-bond donors / acceptors	1 / 3
TPSA	40.6 Å²
Synonyms	1-[2-[(2,4-Dimethylphenyl)thio]phenyl]piperazine, 1-[2-(2,4-Dimethylphenylsulfanyl)phenyl]piperazine, Brintellix, Trintellix, 1-{2-[(2,4-dimethylphenyl)sulfanyl]phenyl}piperazine, Piperazine, 1-[2-[(2,4-dimethylphenyl)thio]phenyl]-, Piperazine, 1-(2-((2,4-dimethylphenyl)thio)phenyl)-, 1-(2-(2,4-dimethylphenylsulfanyl)phenyl)piperazine, 1-(2-((2,4-Dimethylphenyl)sulfanyl)phenyl}piperazine, 1-(2-((2,4-Dimethylphenyl)thio)phenyl)piperazine, Vortioxetine free base, Vortioxetine (USAN)

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Environmental hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H361Suspected of damaging fertility or the unborn child
H371May cause damage to organs
H373May causes damage to organs through prolonged or repeated exposure
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects

Precautionary statements: P203, P260, P264, P270, P273, P280, P301 + P317, P308 + P316, P318, P319, P330, P391, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Vortioxetine?

The CAS Registry Number of Vortioxetine is 508233-74-7. It is also known as 1-[2-[(2,4-Dimethylphenyl)thio]phenyl]piperazine, 1-[2-(2,4-Dimethylphenylsulfanyl)phenyl]piperazine, Brintellix.

What is the molecular formula and molecular weight of Vortioxetine?

Vortioxetine has the molecular formula C18H22N2S and a molecular weight of 298.4 g/mol. Its IUPAC name is 1-[2-(2,4-dimethylphenyl)sulfanylphenyl]piperazine.

What is Vortioxetine used for?

Vortioxetine is supplied as a characterised reference material related to Vortioxetine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Vortioxetine can I order?

We supply Vortioxetine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Vortioxetine?

Yes. Every lot of Vortioxetine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Vortioxetine be shipped internationally?

Yes. Vortioxetine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.