N-Acetyl Mesalazine

About N-Acetyl Mesalazine

N-Acetyl Mesalazine is a metabolite or degradation product of Mesalamine carrying the CAS registry number 51-59-2. Formula C9H9NO4, molecular weight 195.17 g/mol. Its systematic (IUPAC) name is 5-acetamido-2-hydroxybenzoic acid. Common synonyms include N-Acetyl Mesalamine and N-Acetyl-5-aminosalicylic acid.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Analytical teams use this compound to identify metabolites and degradants of Mesalamine, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Mesalamine

View every impurity, metabolite and intermediate we list for Mesalamine.

Mesalamine impurities

Specifications & identifiers

Chemical identifiers
Product name	N-Acetyl Mesalazine
Catalogue No.	VQ-026613
CAS Number	51-59-2
IUPAC name	5-acetamido-2-hydroxybenzoic acid
Molecular formula	C₉H₉NO₄
Molecular weight	195.17 g/mol
Exact mass	195.0532
Grade	Reference Standard
HSN code	38229090
InChIKey	GEFDRROBUCULOD-UHFFFAOYSA-N
SMILES	CC(=O)NC1=CC(=C(C=C1)O)C(=O)O
PubChem CID	65512

Physical properties
Physical form	Solid
LogP (XLogP3)	1.6
H-bond donors / acceptors	3 / 4
TPSA	86.6 Å²
Synonyms	N-Acetyl Mesalamine, N-Acetyl-5-aminosalicylic acid, 5-Acetamidosalicylic acid, Benzoic acid, 5-(acetylamino)-2-hydroxy-, Salicylic acid, 5-acetamido-, CJ-46A, 5-(acetylamino)-2-hydroxybenzoic acid, 5-(Acetylamino)salicylic acid, 2-Hydroxy-5-acetylaminobenzoic acid, 5-Acetaminosalicylic Acid, 2-Hydroxy-5-(acetylamino)benzoic acid, 5-Acetylamino-salicylic acid

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H319Causes serious eye irritation

Precautionary statements: P264, P264 + P265, P270, P280, P301 + P317, P305 + P351 + P338, P330, P337 + P317, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Acetyl Mesalazine?

The CAS Registry Number of N-Acetyl Mesalazine is 51-59-2. It is also known as N-Acetyl Mesalamine, N-Acetyl-5-aminosalicylic acid, 5-Acetamidosalicylic acid.

What is the molecular formula and molecular weight of N-Acetyl Mesalazine?

N-Acetyl Mesalazine has the molecular formula C9H9NO4 and a molecular weight of 195.17 g/mol. Its IUPAC name is 5-acetamido-2-hydroxybenzoic acid.

What is N-Acetyl Mesalazine used for?

N-Acetyl Mesalazine is supplied as a characterised reference material related to Mesalamine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Acetyl Mesalazine can I order?

We supply N-Acetyl Mesalazine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Acetyl Mesalazine?

Yes. Every lot of N-Acetyl Mesalazine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Acetyl Mesalazine be shipped internationally?

Yes. N-Acetyl Mesalazine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.