Neostigmine methyl sulphate

Name: Neostigmine methyl sulphate
Brand: Vaqora Chemicals
SKU: VQ-026869

About Neostigmine methyl sulphate

Vaqora Chemicals supplies Neostigmine methyl sulphate, an impurity of Neostigmine registered under CAS number 51-60-5. Its molecular formula is C13H22N2O6S and its molecular weight is 334.39 g/mol. Common synonyms include Neostigmine Methyl Sulfate and Neostigmine Metilsulfate.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

As a characterised impurity of Neostigmine, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Neostigmine methyl sulphate in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Neostigmine

View every impurity, metabolite and intermediate we list for Neostigmine.

Neostigmine impurities

Specifications & identifiers

Chemical identifiers
Product name	Neostigmine methyl sulphate
Catalogue No.	VQ-026869
CAS Number	51-60-5
IUPAC name	[3-(dimethylcarbamoyloxy)phenyl]-trimethylazanium;methyl sulfate
Molecular formula	C₁₃H₂₂N₂O₆S
Molecular weight	334.39 g/mol
Exact mass	334.1199
Grade	Reference Standard
HSN code	38229090
InChIKey	OSZNNLWOYWAHSS-UHFFFAOYSA-M
SMILES	CN(C)C(=O)OC1=CC=CC(=C1)[N+](C)(C)C.COS(=O)(=O)[O-]
PubChem CID	5824

Physical properties
Physical form	Solid
H-bond donors / acceptors	0 / 6
TPSA	104 Å²
Synonyms	Neostigmine Methyl Sulfate, Neostigmine Metilsulfate, Syntostigmin, Proserine, (m-Hydroxyphenyl)trimethylammonium methyl sulfate dimethylcarbamate, Neostigmini metilsulfas, Benzenaminium, 3-(((dimethylamino)carbonyl)oxy)-N,N,N-trimethyl-, methyl sulfate, Robinul-neostig, Stiglyn 1:500, Methylsulfate, Neostigmine, 3-(Dimethylcarbamoyloxy)-N,N,N-trimethylanilinium methyl sulfate

Safety & hazard information (GHS)

Toxic

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H300Fatal if swallowed
H301Toxic if swallowed
H310Fatal in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H330Fatal if inhaled
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335May cause respiratory irritation

Precautionary statements: P233, P260, P261, P262, P264, P264 + P265, P270, P271, P280, P284, P301 + P316, P302 + P352, P304 + P340, P305 + P351 + P338, P316, P319, P320, P321, P330, P332 + P317, P337 + P317, P342 + P316, P361 + P364, P362 + P364

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Neostigmine methyl sulphate?

The CAS Registry Number of Neostigmine methyl sulphate is 51-60-5. It is also known as Neostigmine Methyl Sulfate, Neostigmine Metilsulfate, Syntostigmin.

What is the molecular formula and molecular weight of Neostigmine methyl sulphate?

Neostigmine methyl sulphate has the molecular formula C13H22N2O6S and a molecular weight of 334.39 g/mol.

What is Neostigmine methyl sulphate used for?

Neostigmine methyl sulphate is supplied as a characterised reference material related to Neostigmine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Neostigmine methyl sulphate can I order?

We supply Neostigmine methyl sulphate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Neostigmine methyl sulphate?

Yes. Every lot of Neostigmine methyl sulphate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Neostigmine methyl sulphate be shipped internationally?

Yes. Neostigmine methyl sulphate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.