4-Hydroxy-3-pyridinesulfonic Acid

About 4-Hydroxy-3-pyridinesulfonic Acid

4-Hydroxy-3-pyridinesulfonic Acid is a metabolite or degradation product of N methylpyrrolidone carrying the CAS registry number 51498-37-4. Its molecular formula is C5H5NO4S and its molecular weight is 175.16 g/mol. Systematically, it is named 4-oxo-1H-pyridine-3-sulfonic acid. Common synonyms include 4-Hydroxy-3-pyridinesulphonic acid and 4-Hydroxypyridine-3-sulfonic Acid.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

It is used in metabolite identification, stability-indicating method development and impurity profiling of N methylpyrrolidone, as well as in QC testing and ANDA/DMF documentation. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling
Fine chemical synthesis

Industries

Related to N methylpyrrolidone

View every impurity, metabolite and intermediate we list for N methylpyrrolidone.

N methylpyrrolidone impurities

Specifications & identifiers

Chemical identifiers
Product name	4-Hydroxy-3-pyridinesulfonic Acid
Catalogue No.	VQ-040056
CAS Number	51498-37-4
IUPAC name	4-oxo-1H-pyridine-3-sulfonic acid
Molecular formula	C₅H₅NO₄S
Molecular weight	175.16 g/mol
Exact mass	174.9939
Grade	Reference Standard
HSN code	38229090
InChIKey	AZRCSTMIVMQIPR-UHFFFAOYSA-N
SMILES	C1=CNC=C(C1=O)S(=O)(=O)O
PubChem CID	3016673

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.4
H-bond donors / acceptors	2 / 5
TPSA	91.9 Å²
Synonyms	4-Hydroxy-3-pyridinesulphonic acid, 4-Hydroxypyridine-3-sulfonic Acid, 4-Hydroxypyridine-3-sulfonicacid, 3-Pyridinesulfonic acid, 4-hydroxy-, 4-Pyridinol-3-sulfonic Acid, 4-hydroxy-pyridine-3-sulphonic acid, 4-oxo-1,4-dihydropyridine-3-sulfonic acid

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Signal word: Danger

Hazard statements

H314Causes severe skin burns and eye damage
H315Causes skin irritation
H318Causes serious eye damage
H319Causes serious eye irritation

Precautionary statements: P260, P264, P264 + P265, P280, P301 + P330 + P331, P302 + P352, P302 + P361 + P354, P304 + P340, P305 + P351 + P338, P305 + P354 + P338, P316, P317, P321, P332 + P317, P337 + P317, P362 + P364, P363, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-Hydroxy-3-pyridinesulfonic Acid?

The CAS Registry Number of 4-Hydroxy-3-pyridinesulfonic Acid is 51498-37-4. It is also known as 4-Hydroxy-3-pyridinesulphonic acid, 4-Hydroxypyridine-3-sulfonic Acid, 4-Hydroxypyridine-3-sulfonicacid.

What is the molecular formula and molecular weight of 4-Hydroxy-3-pyridinesulfonic Acid?

4-Hydroxy-3-pyridinesulfonic Acid has the molecular formula C5H5NO4S and a molecular weight of 175.16 g/mol. Its IUPAC name is 4-oxo-1H-pyridine-3-sulfonic acid.

What is 4-Hydroxy-3-pyridinesulfonic Acid used for?

4-Hydroxy-3-pyridinesulfonic Acid is supplied as a characterised reference material related to N methylpyrrolidone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-Hydroxy-3-pyridinesulfonic Acid can I order?

We supply 4-Hydroxy-3-pyridinesulfonic Acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-Hydroxy-3-pyridinesulfonic Acid?

Yes. Every lot of 4-Hydroxy-3-pyridinesulfonic Acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-Hydroxy-3-pyridinesulfonic Acid be shipped internationally?

Yes. 4-Hydroxy-3-pyridinesulfonic Acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.