2-Bromo-4-Nitroanisole

Name: 2-Bromo-4-Nitroanisole
Brand: Vaqora Chemicals
SKU: VQ-048182

About 2-Bromo-4-Nitroanisole

Vaqora Chemicals supplies 2-Bromo-4-Nitroanisole, a process intermediate or related compound of Eltrombopag registered under CAS number 5197-28-4. Its molecular formula is C7H6BrNO3 and its molecular weight is 232.03 g/mol. Systematically, it is named 2-bromo-1-methoxy-4-nitrobenzene. It is also known as Anisole, 2-bromo-4-nitro- or 3-Bromo-4-methoxynitrobenzene.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Danger” with 4 hazard statements. Review the Safety Data Sheet before use.

It is a process intermediate or related compound in the synthesis of Eltrombopag, useful for route development, impurity fate-and-purge studies and analytical method development. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer 2-Bromo-4-Nitroanisole in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Eltrombopag

View every impurity, metabolite and intermediate we list for Eltrombopag.

Eltrombopag impurities

Specifications & identifiers

Chemical identifiers
Product name	2-Bromo-4-Nitroanisole
Catalogue No.	VQ-048182
CAS Number	5197-28-4
IUPAC name	2-bromo-1-methoxy-4-nitrobenzene
Molecular formula	C₇H₆BrNO₃
Molecular weight	232.03 g/mol
Exact mass	230.9531
InChIKey	JMUDXQVNBZCQRF-UHFFFAOYSA-N
SMILES	COC1=C(C=C(C=C1)[N+](=O)[O-])Br
PubChem CID	78870

Physical properties
Physical form	Solid
LogP (XLogP3)	2.8
H-bond donors / acceptors	0 / 3
TPSA	55.1 Å²
Synonyms	Anisole, 2-bromo-4-nitro-, 3-Bromo-4-methoxynitrobenzene, 4-Nitro-2-bromanisol, 2-bromo-1-methoxy-4-nitro-benzene, 4-Nitro-2-bromoanisole

Safety & hazard information (GHS)

Toxic

Harmful / irritant

Signal word: Danger

Hazard statements

H301+H311+H331Toxic if swallowed, in contact with skin or if inhaled
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P262, P264, P264 + P265, P270, P271, P280, P301 + P316, P302 + P352, P304 + P340, P305 + P351 + P338, P316, P319, P321, P330, P332 + P317, P337 + P317, P361 + P364, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2-Bromo-4-Nitroanisole?

The CAS Registry Number of 2-Bromo-4-Nitroanisole is 5197-28-4. It is also known as Anisole, 2-bromo-4-nitro-, 3-Bromo-4-methoxynitrobenzene, 4-Nitro-2-bromanisol.

What is the molecular formula and molecular weight of 2-Bromo-4-Nitroanisole?

2-Bromo-4-Nitroanisole has the molecular formula C7H6BrNO3 and a molecular weight of 232.03 g/mol. Its IUPAC name is 2-bromo-1-methoxy-4-nitrobenzene.

What is 2-Bromo-4-Nitroanisole used for?

2-Bromo-4-Nitroanisole is supplied as a characterised reference material related to Eltrombopag. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2-Bromo-4-Nitroanisole can I order?

We supply 2-Bromo-4-Nitroanisole, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-Bromo-4-Nitroanisole?

Yes. Every lot of 2-Bromo-4-Nitroanisole is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-Bromo-4-Nitroanisole be shipped internationally?

Yes. 2-Bromo-4-Nitroanisole is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.