Prednisolone Acetate

About Prednisolone Acetate

Prednisolone Acetate is a process intermediate or related compound of Prednisolone carrying the CAS registry number 52-21-1 with a typical assay of 97.4%. Its molecular formula is C23H30O6 and its molecular weight is 402.5 g/mol. Alternative names: Cormalone and Cortipred.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Danger” with 5 hazard statements. Review the Safety Data Sheet before use.

Process chemists and analysts use it when developing synthetic routes to Prednisolone, tracking process-related impurities and validating analytical methods. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Prednisolone Acetate is dispatched with a Certificate of Analysis (COA) to destinations worldwide. This item is currently in stock for prompt dispatch.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Prednisolone

View every impurity, metabolite and intermediate we list for Prednisolone.

Prednisolone impurities

Specifications & identifiers

Chemical identifiers
Product name	Prednisolone Acetate
Catalogue No.	VQ-013745
CAS Number	52-21-1
IUPAC name	[2-[(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate
Molecular formula	C₂₃H₃₀O₆
Molecular weight	402.5 g/mol
Exact mass	402.2042
Grade	Reference Standard
Purity / assay	97.4%
InChIKey	LRJOMUJRLNCICJ-JZYPGELDSA-N
SMILES	CC(=O)OCC(=O)[C@]1(CC[C@@H]2[C@@]1(C[C@@H]([C@H]3[C@H]2CCC4=CC(=O)C=C[C@]34C)O)C)O
PubChem CID	5834

Physical properties
Physical form	Solid
LogP (XLogP3)	2.4
H-bond donors / acceptors	2 / 6
TPSA	101 Å²
Synonyms	(11β)-21-(Acetyloxy)-11,17-dihydroxypregna-1,4-diene-3,20-dione, 21-(Acetoxy)-11β,17α-dihydroxypregna-1,4-diene-3,20-dione, Cormalone, Cortipred, Deltilen, Econopred, Falcon, Meticortelone Acetate, Predalone 50, Prediacortin, Predicort, Prednidoren

Safety & hazard information (GHS)

Toxic

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H300Fatal if swallowed
H319Causes serious eye irritation
H360May damage fertility or the unborn child
H361Suspected of damaging fertility or the unborn child
H373May causes damage to organs through prolonged or repeated exposure

Precautionary statements: P203, P260, P264, P264 + P265, P270, P280, P301 + P316, P305 + P351 + P338, P318, P319, P321, P330, P337 + P317, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Prednisolone Acetate?

The CAS Registry Number of Prednisolone Acetate is 52-21-1. It is also known as (11β)-21-(Acetyloxy)-11,17-dihydroxypregna-1,4-diene-3,20-dione, 21-(Acetoxy)-11β,17α-dihydroxypregna-1,4-diene-3,20-dione, Cormalone.

What is the molecular formula and molecular weight of Prednisolone Acetate?

Prednisolone Acetate has the molecular formula C23H30O6 and a molecular weight of 402.5 g/mol. Its IUPAC name is [2-[(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate.

What is Prednisolone Acetate used for?

Prednisolone Acetate is supplied as a characterised reference material related to Prednisolone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Prednisolone Acetate can I order?

We supply Prednisolone Acetate in Reference Standard (97.4%) grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Prednisolone Acetate?

Yes. Every lot of Prednisolone Acetate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Prednisolone Acetate be shipped internationally?

Yes. Prednisolone Acetate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.