6a,9a-Difluoroprednisolone 21-Acetate

Name: 6a,9a-Difluoroprednisolone 21-Acetate
Brand: Vaqora Chemicals
SKU: VQ-027594

About 6a,9a-Difluoroprednisolone 21-Acetate

Listed under CAS 52-70-0, 6a,9a-Difluoroprednisolone 21-Acetate is an impurity of Difluprednate available from Vaqora Chemicals. With the molecular formula C23H28F2O6, it has a molar mass of 438.5 g/mol. Alternative names: 6alpha,9alpha-Difluoroprednisolone-21-Acetate and 6α,9α-Difluoroprednisolone 21-Acetate.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Difluprednate to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 6a,9a-Difluoroprednisolone 21-Acetate in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Difluprednate

View every impurity, metabolite and intermediate we list for Difluprednate.

Difluprednate impurities

Specifications & identifiers

Chemical identifiers
Product name	6a,9a-Difluoroprednisolone 21-Acetate
Catalogue No.	VQ-027594
CAS Number	52-70-0
IUPAC name	[2-[(6S,8S,9R,10S,11S,13S,14S,17R)-6,9-difluoro-11,17-dihydroxy-10,13-dimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate
Molecular formula	C₂₃H₂₈F₂O₆
Molecular weight	438.5 g/mol
Exact mass	438.1854
Grade	Reference Standard
HSN code	38229090
InChIKey	LAAFISZDLHQNFS-WGFKBPOKSA-N
SMILES	CC(=O)OCC(=O)[C@]1(CC[C@@H]2[C@@]1(C[C@@H]([C@]3([C@H]2C[C@@H](C4=CC(=O)C=C[C@@]43C)F)F)O)C)O
PubChem CID	101528

Physical properties
Physical form	Solid
LogP (XLogP3)	2
H-bond donors / acceptors	2 / 8
TPSA	101 Å²
Synonyms	6alpha,9alpha-Difluoroprednisolone-21-Acetate, 6α,9α-Difluoroprednisolone 21-Acetate, (6alpha,11beta)-21-(Acetyloxy)-6,9-difluoro-11,17-dihydroxypregna-1,4-diene-3,20-dione, 6alpha,9-Difluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 21-acetate, Difluoroprednisolone-21-Acetate, (6, A,11, A)-21-(Acetyloxy)-6,9-difluoro-11,17-dihydroxypregna-1,4-diene-3,20-dione, Pregna-1,4-diene-3,20-dione, 6alpha,9-difluoro-11beta,17,21-trihydroxy-, 21-acetate, 6alpha,9alpha-Difluoroprednisolone 21-acetate, 6,9-Difluoro-11,17-dihydroxy-3,20-dioxopregna-1,4-dien-21-yl acetate, 6alpha,9-Difluoro-11beta,17-dihydroxy-3,20-dioxopregna-1,4-dien-21-yl acetate

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 6a,9a-Difluoroprednisolone 21-Acetate?

The CAS Registry Number of 6a,9a-Difluoroprednisolone 21-Acetate is 52-70-0. It is also known as 6alpha,9alpha-Difluoroprednisolone-21-Acetate, 6α,9α-Difluoroprednisolone 21-Acetate, (6alpha,11beta)-21-(Acetyloxy)-6,9-difluoro-11,17-dihydroxypregna-1,4-diene-3,20-dione.

What is the molecular formula and molecular weight of 6a,9a-Difluoroprednisolone 21-Acetate?

6a,9a-Difluoroprednisolone 21-Acetate has the molecular formula C23H28F2O6 and a molecular weight of 438.5 g/mol.

What is 6a,9a-Difluoroprednisolone 21-Acetate used for?

6a,9a-Difluoroprednisolone 21-Acetate is supplied as a characterised reference material related to Difluprednate. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 6a,9a-Difluoroprednisolone 21-Acetate can I order?

We supply 6a,9a-Difluoroprednisolone 21-Acetate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 6a,9a-Difluoroprednisolone 21-Acetate?

Yes. Every lot of 6a,9a-Difluoroprednisolone 21-Acetate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 6a,9a-Difluoroprednisolone 21-Acetate be shipped internationally?

Yes. We export 6a,9a-Difluoroprednisolone 21-Acetate worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.