Hesperetin

About Hesperetin

Hesperetin is an impurity of Diosmin carrying the CAS registry number 520-33-2. The compound has the formula C16H14O6, corresponding to a molecular weight of 302.28 g/mol. Its systematic (IUPAC) name is (2S)-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-2,3-dihydrochromen-4-one. It is also known as Hesperitin or 3',5,7-Trihydroxy-4'-methoxyflavanone.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

This Diosmin impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer Hesperetin in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Diosmin

View every impurity, metabolite and intermediate we list for Diosmin.

Diosmin impurities

Specifications & identifiers

Chemical identifiers
Product name	Hesperetin
Catalogue No.	VQ-022403
CAS Number	520-33-2
IUPAC name	(2S)-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-2,3-dihydrochromen-4-one
Molecular formula	C₁₆H₁₄O₆
Molecular weight	302.28 g/mol
Exact mass	302.079
Grade	Reference Standard
HSN code	38229090
InChIKey	AIONOLUJZLIMTK-AWEZNQCLSA-N
SMILES	COC1=C(C=C(C=C1)[C@@H]2CC(=O)C3=C(C=C(C=C3O2)O)O)O
PubChem CID	72281

Physical properties
Physical form	Solid
LogP (XLogP3)	2.4
H-bond donors / acceptors	3 / 6
TPSA	96.2 Å²
Synonyms	Hesperitin, 3',5,7-Trihydroxy-4'-methoxyflavanone, 5,7,3'-Trihydroxy-4'-methoxyflavanone, (-)-(S)-hesperetin, Eriodictyol 4'-monomethyl ether, 4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-, (S)-, (S)-2,3-dihydro-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one, Flavanone, 3',5,7-trihydroxy-4'-methoxy-, 4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-, (2S)-, (S)-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)chroman-4-one

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Hesperetin?

The CAS Registry Number of Hesperetin is 520-33-2. It is also known as Hesperitin, 3',5,7-Trihydroxy-4'-methoxyflavanone, 5,7,3'-Trihydroxy-4'-methoxyflavanone.

What is the molecular formula and molecular weight of Hesperetin?

Hesperetin has the molecular formula C16H14O6 and a molecular weight of 302.28 g/mol. Its IUPAC name is (2S)-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-2,3-dihydrochromen-4-one.

What is Hesperetin used for?

Hesperetin is supplied as a characterised reference material related to Diosmin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Hesperetin can I order?

We supply Hesperetin in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Hesperetin?

Yes. Every lot of Hesperetin is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Hesperetin be shipped internationally?

Yes. We export Hesperetin worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.