N-(2,6-Dimethylphenyl)-1-piperazineacetamide

About N-(2,6-Dimethylphenyl)-1-piperazineacetamide

N-(2,6-Dimethylphenyl)-1-piperazineacetamide is a process intermediate or related compound of Ranolazine carrying the CAS registry number 5294-61-1. The compound has the formula C14H21N3O, corresponding to a molecular weight of 247.34 g/mol. The IUPAC name is N-(2,6-dimethylphenyl)-2-piperazin-1-ylacetamide. Common synonyms include N-(2,6-Dimethylphenyl)-2-piperazinylacetamide and 1-Piperazineaceto-2',6'-xylidide.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Process chemists and analysts use it when developing synthetic routes to Ranolazine, tracking process-related impurities and validating analytical methods. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer N-(2,6-Dimethylphenyl)-1-piperazineacetamide in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. Stock is available for quick dispatch.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Ranolazine

View every impurity, metabolite and intermediate we list for Ranolazine.

Ranolazine impurities

Specifications & identifiers

Chemical identifiers
Product name	N-(2,6-Dimethylphenyl)-1-piperazineacetamide
Catalogue No.	VQ-013584
CAS Number	5294-61-1
Other CAS	3398-91-2
IUPAC name	N-(2,6-dimethylphenyl)-2-piperazin-1-ylacetamide
Molecular formula	C₁₄H₂₁N₃O
Molecular weight	247.34 g/mol
Exact mass	247.1685
Grade	Reference Standard
HSN code	2933
InChIKey	NJKRFQIWDJSYOK-UHFFFAOYSA-N
SMILES	CC1=C(C(=CC=C1)C)NC(=O)CN2CCNCC2
PubChem CID	2608606

Physical properties
Physical form	Solid
LogP (XLogP3)	1.2
H-bond donors / acceptors	2 / 3
TPSA	44.4 Å²
Synonyms	4-[(2,6-Dimethylphenyl)aminocarbonylmethyl]piperazine, N-(2,6-Dimethylphenyl)-2-(1-piperazinyl)acetamide, N-(2,6-Dimethylphenyl)-2-piperazinylacetamide, 1-Piperazineaceto-2',6'-xylidide, N-(2,6-dimethylphenyl)-2-(piperazin-1-yl)acetamide, CVT-2738, 1-Piperazineacetamide, N-(2,6-dimethylphenyl)-, CVT 2738, 4-((2,6-Dimethylphenyl)aminocarbonylmethyl)piperazine, 2-(1-Piperazinyl)-N-(2,6-dimethylphenyl)acetamide (dmpipa), n-(2,6-dimethylphenyl)-1-piperazineacetamide, N-(2,6-Diphenylmethyl)-1-piperazine acetylamine

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H317May cause an allergic skin reaction
H318Causes serious eye damage
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P272, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P305 + P354 + P338, P317, P319, P321, P330, P332 + P317, P333 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-(2,6-Dimethylphenyl)-1-piperazineacetamide?

The CAS Registry Number of N-(2,6-Dimethylphenyl)-1-piperazineacetamide is 5294-61-1. It is also known as 4-[(2,6-Dimethylphenyl)aminocarbonylmethyl]piperazine, N-(2,6-Dimethylphenyl)-2-(1-piperazinyl)acetamide, N-(2,6-Dimethylphenyl)-2-piperazinylacetamide.

What is the molecular formula and molecular weight of N-(2,6-Dimethylphenyl)-1-piperazineacetamide?

N-(2,6-Dimethylphenyl)-1-piperazineacetamide has the molecular formula C14H21N3O and a molecular weight of 247.34 g/mol. Its IUPAC name is N-(2,6-dimethylphenyl)-2-piperazin-1-ylacetamide.

What is N-(2,6-Dimethylphenyl)-1-piperazineacetamide used for?

N-(2,6-Dimethylphenyl)-1-piperazineacetamide is supplied as a characterised reference material related to Ranolazine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-(2,6-Dimethylphenyl)-1-piperazineacetamide can I order?

We supply N-(2,6-Dimethylphenyl)-1-piperazineacetamide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-(2,6-Dimethylphenyl)-1-piperazineacetamide?

Yes. Every lot of N-(2,6-Dimethylphenyl)-1-piperazineacetamide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-(2,6-Dimethylphenyl)-1-piperazineacetamide be shipped internationally?

Yes. N-(2,6-Dimethylphenyl)-1-piperazineacetamide is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.