(R)-8-(Benzyloxy)-5-(2-bromo-1-hydroxyethyl)q… 530084-79-8

About (R)-8-(Benzyloxy)-5-(2-bromo-1-hydroxyethyl)quinolin-2(1H)-one

(R)-8-(Benzyloxy)-5-(2-bromo-1-hydroxyethyl)quinolin-2(1H)-one is a metabolite or degradation product of Indacaterol carrying the CAS registry number 530084-79-8. With the molecular formula C18H16BrNO3, it has a molar mass of 374.2 g/mol. Its systematic (IUPAC) name is 5-[(1R)-2-bromo-1-hydroxyethyl]-8-phenylmethoxy-1H-quinolin-2-one.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Danger” with 4 hazard statements. Review the Safety Data Sheet before use.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Indacaterol, as well as in QC testing and ANDA/DMF documentation. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer (R)-8-(Benzyloxy)-5-(2-bromo-1-hydroxyethyl)quinolin-2(1H)-one in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Indacaterol

View every impurity, metabolite and intermediate we list for Indacaterol.

Indacaterol impurities

Specifications & identifiers

Chemical identifiers
Product name	(R)-8-(Benzyloxy)-5-(2-bromo-1-hydroxyethyl)quinolin-2(1H)-one
Catalogue No.	VQ-031192
CAS Number	530084-79-8
IUPAC name	5-[(1R)-2-bromo-1-hydroxyethyl]-8-phenylmethoxy-1H-quinolin-2-one
Molecular formula	C₁₈H₁₆BrNO₃
Molecular weight	374.2 g/mol
Exact mass	373.0314
Grade	Reference Standard
HSN code	38229090
InChIKey	GNFMSZCSSUZAGV-HNNXBMFYSA-N
SMILES	C1=CC=C(C=C1)COC2=C3C(=C(C=C2)[C@H](CBr)O)C=CC(=O)N3
PubChem CID	11530884

Physical properties
Physical form	Solid
LogP (XLogP3)	2.7
H-bond donors / acceptors	2 / 3
TPSA	58.6 Å²
Synonyms	ICM-I_[(R)-8-(benzyloxy)-5-(2-bromo-1-hydroxyethyl) quinolin-2(1H)-one], 5-[(1R)-2-Bromo-1-hydroxyethyl]-8-(phenylmethoxy)-2(1H)-quinolinone, 5-((1R)-2-bromo-1-hydroxyethyl)-8-phenylmethoxy-1H-quinolin-2-one, 5-((1R)-2-Bromo-1-hydroxyethyl)-8-(phenylmethoxy)-2(1H)-quinolinone, 8-Benzyloxy-5-((R)-2-bromo-1-hydroxyethyl)-1H-quinolinone, 8-(benzyloxy)-5-[(1R)-2-bromo-1-hydroxyethyl]quinolin-2(1H)-one, (R)-8-Benzyloxy-5-(2-bromo-1-hydroxyethyl)carbostyril, 8-benzyloxy-5-[(r)-(2-bromo-1-hydroxyethyl)]-carbostyril, 8-benzyloxy-5-((R)-2-bromo-1-hyroxyethyl)-1H-quinolin-2-one, 5-(2-Bromo -(R)-1-hydroxyethyl)-8-benzyloxy-2(1H)-quinolinone, 8-Benzyloxy-5-((R)-2-bromo -1-hyroxyethyl)-1H-quinolin-2-one

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H317May cause an allergic skin reaction
H318Causes serious eye damage
H341Suspected of causing genetic defects
H412Harmful to aquatic life with long lasting effects

Precautionary statements: P203, P261, P264 + P265, P272, P273, P280, P302 + P352, P305 + P354 + P338, P317, P318, P321, P333 + P317, P362 + P364, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (R)-8-(Benzyloxy)-5-(2-bromo-1-hydroxyethyl)quinolin-2(1H)-one?

The CAS Registry Number of (R)-8-(Benzyloxy)-5-(2-bromo-1-hydroxyethyl)quinolin-2(1H)-one is 530084-79-8. It is also known as ICM-I_[(R)-8-(benzyloxy)-5-(2-bromo-1-hydroxyethyl) quinolin-2(1H)-one], 5-[(1R)-2-Bromo-1-hydroxyethyl]-8-(phenylmethoxy)-2(1H)-quinolinone, 5-((1R)-2-bromo-1-hydroxyethyl)-8-phenylmethoxy-1H-quinolin-2-one.

What is the molecular formula and molecular weight of (R)-8-(Benzyloxy)-5-(2-bromo-1-hydroxyethyl)quinolin-2(1H)-one?

(R)-8-(Benzyloxy)-5-(2-bromo-1-hydroxyethyl)quinolin-2(1H)-one has the molecular formula C18H16BrNO3 and a molecular weight of 374.2 g/mol. Its IUPAC name is 5-[(1R)-2-bromo-1-hydroxyethyl]-8-phenylmethoxy-1H-quinolin-2-one.

What is (R)-8-(Benzyloxy)-5-(2-bromo-1-hydroxyethyl)quinolin-2(1H)-one used for?

(R)-8-(Benzyloxy)-5-(2-bromo-1-hydroxyethyl)quinolin-2(1H)-one is supplied as a characterised reference material related to Indacaterol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (R)-8-(Benzyloxy)-5-(2-bromo-1-hydroxyethyl)quinolin-2(1H)-one can I order?

We supply (R)-8-(Benzyloxy)-5-(2-bromo-1-hydroxyethyl)quinolin-2(1H)-one in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (R)-8-(Benzyloxy)-5-(2-bromo-1-hydroxyethyl)quinolin-2(1H)-one?

Yes. Every lot of (R)-8-(Benzyloxy)-5-(2-bromo-1-hydroxyethyl)quinolin-2(1H)-one is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (R)-8-(Benzyloxy)-5-(2-bromo-1-hydroxyethyl)quinolin-2(1H)-one be shipped internationally?

Yes. (R)-8-(Benzyloxy)-5-(2-bromo-1-hydroxyethyl)quinolin-2(1H)-one is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.