Digoxin - Impurity J | CAS 5355-48-6

Name: Digoxin - Impurity J
Brand: Vaqora Chemicals
SKU: VQ-025319

About Digoxin - Impurity J

Digoxin - Impurity J (CAS 5355-48-6) is an impurity of Digoxin offered by Vaqora Chemicals. With the molecular formula C43H66O15, it has a molar mass of 823.0 g/mol. Alternative names: Digoxin EP Impurity J and β-Acetyl Digoxin.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Digoxin to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Digoxin - Impurity J in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Digoxin

View every impurity, metabolite and intermediate we list for Digoxin.

Digoxin impurities

Specifications & identifiers

Chemical identifiers
Product name	Digoxin - Impurity J
Catalogue No.	VQ-025319
CAS Number	5355-48-6
IUPAC name	[(2R,3S,4S,6S)-6-[(2R,3S,4S,6S)-6-[(2R,3S,4S,6R)-6-[[(3S,5R,8R,9S,10S,12R,13S,14S,17R)-12,14-dihydroxy-10,13-dimethyl-17-(5-oxo-2H-furan-3-yl)-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-yl]oxy]-4-hydroxy-2-methyloxan-3-yl]oxy-4-hydroxy-2-methyloxan-3-yl]oxy-4-hydroxy-2-methyloxan-3-yl] acetate
Molecular formula	C₄₃H₆₆O₁₅
Molecular weight	823 g/mol
Exact mass	822.4402
Grade	Reference Standard
HSN code	38229090
InChIKey	NREAGDHHMSOWKZ-DXJNJSHLSA-N
SMILES	C[C@@H]1[C@H]([C@H](C[C@@H](O1)O[C@H]2CC[C@]3([C@@H](C2)CC[C@@H]4[C@@H]3C[C@H]([C@]5([C@@]4(CC[C@@H]5C6=CC(=O)OC6)O)C)O)C)O)O[C@H]7C[C@@H]([C@@H]([C@H](O7)C)O[C@H]8C[C@@H]([C@@H]([C@H](O8)C)OC(=O)C)O)O
PubChem CID	10350481

Physical properties
Physical form	Solid
LogP (XLogP3)	1.8
H-bond donors / acceptors	5 / 15
TPSA	209 Å²
Synonyms	Digoxin EP Impurity J, β-Acetyl Digoxin, beta-Acetyldigoxin, Novodigal, 4'''-Acetyldigoxin, beta Acetyldigoxin, Acetyldigoxin beta, b-Acetyl digoxin, Acetyldigoxin beta isomer, 16'-Acetyldigoxin, Digoxin Didier, Cor-Puren

Safety & hazard information (GHS)

Corrosive

Toxic

Signal word: Danger

Hazard statements

H300+H330Fatal if swallowed or if inhaled
H300Fatal if swallowed
H314Causes severe skin burns and eye damage
H330Fatal if inhaled

Precautionary statements: P260, P264, P270, P271, P280, P284, P301 + P316, P301 + P330 + P331, P302 + P361 + P354, P304 + P340, P305 + P354 + P338, P316, P320, P321, P330, P363, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Digoxin - Impurity J?

The CAS Registry Number of Digoxin - Impurity J is 5355-48-6. It is also known as Digoxin EP Impurity J, β-Acetyl Digoxin, beta-Acetyldigoxin.

What is the molecular formula and molecular weight of Digoxin - Impurity J?

Digoxin - Impurity J has the molecular formula C43H66O15 and a molecular weight of 823 g/mol.

What is Digoxin - Impurity J used for?

Digoxin - Impurity J is supplied as a characterised reference material related to Digoxin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Digoxin - Impurity J can I order?

We supply Digoxin - Impurity J in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Digoxin - Impurity J?

Yes. Every lot of Digoxin - Impurity J is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Digoxin - Impurity J be shipped internationally?

Yes. Digoxin - Impurity J is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.