3-Hydroxy-4-methoxycinnamic Acid

Name: 3-Hydroxy-4-methoxycinnamic Acid
Brand: Vaqora Chemicals
SKU: VQ-036331

About 3-Hydroxy-4-methoxycinnamic Acid

Vaqora Chemicals supplies 3-Hydroxy-4-methoxycinnamic Acid, a metabolite or degradation product of Cinnamic Acid registered under CAS number 537-73-5. Its molecular formula is C10H10O4 and its molecular weight is 194.18 g/mol. Its systematic (IUPAC) name is (E)-3-(3-hydroxy-4-methoxyphenyl)prop-2-enoic acid. It is also known as Isoferulic Acid or Hesperetic acid.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Cinnamic Acid, as well as in QC testing and ANDA/DMF documentation. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 3-Hydroxy-4-methoxycinnamic Acid in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Cinnamic Acid

View every impurity, metabolite and intermediate we list for Cinnamic Acid.

Cinnamic Acid impurities

Specifications & identifiers

Chemical identifiers
Product name	3-Hydroxy-4-methoxycinnamic Acid
Catalogue No.	VQ-036331
CAS Number	537-73-5
IUPAC name	(E)-3-(3-hydroxy-4-methoxyphenyl)prop-2-enoic acid
Molecular formula	C₁₀H₁₀O₄
Molecular weight	194.18 g/mol
Exact mass	194.0579
Grade	Reference Standard
HSN code	38229090
InChIKey	QURCVMIEKCOAJU-HWKANZROSA-N
SMILES	COC1=C(C=C(C=C1)/C=C/C(=O)O)O
PubChem CID	736186

Physical properties
Physical form	Solid
LogP (XLogP3)	1.5
H-bond donors / acceptors	2 / 4
TPSA	66.8 Å²
Synonyms	Isoferulic Acid, Hesperetic acid, (2E)-3-(3-hydroxy-4-methoxyphenyl)prop-2-enoic acid, 3-(3-Hydroxy-4-methoxyphenyl)-2-propenoic acid, trans-Isoferulic acid, (E)-3-(3-hydroxy-4-methoxyphenyl)acrylic acid, 3-(3-Hydroxy-4-methoxyphenyl)acrylic acid, Isoferulate, 2-Propenoic acid, 3-(3-hydroxy-4-methoxyphenyl)-, Cinnamic acid, 3-hydroxy-4-methoxy-, (E)-3'-Hydroxy-4'-methoxycinnamic acid, trans-3-Hydroxy-4-methoxycinnamic acid

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 3-Hydroxy-4-methoxycinnamic Acid?

The CAS Registry Number of 3-Hydroxy-4-methoxycinnamic Acid is 537-73-5. It is also known as Isoferulic Acid, Hesperetic acid, (2E)-3-(3-hydroxy-4-methoxyphenyl)prop-2-enoic acid.

What is the molecular formula and molecular weight of 3-Hydroxy-4-methoxycinnamic Acid?

3-Hydroxy-4-methoxycinnamic Acid has the molecular formula C10H10O4 and a molecular weight of 194.18 g/mol. Its IUPAC name is (E)-3-(3-hydroxy-4-methoxyphenyl)prop-2-enoic acid.

What is 3-Hydroxy-4-methoxycinnamic Acid used for?

3-Hydroxy-4-methoxycinnamic Acid is supplied as a characterised reference material related to Cinnamic Acid. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 3-Hydroxy-4-methoxycinnamic Acid can I order?

We supply 3-Hydroxy-4-methoxycinnamic Acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 3-Hydroxy-4-methoxycinnamic Acid?

Yes. Every lot of 3-Hydroxy-4-methoxycinnamic Acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 3-Hydroxy-4-methoxycinnamic Acid be shipped internationally?

Yes. 3-Hydroxy-4-methoxycinnamic Acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.