Isobutyl chloroformate, 98%

About Isobutyl chloroformate, 98%

Isobutyl chloroformate is an acylating agent (Synthesis grade) carrying the CAS registry number 543-27-1, specified at 98% purity. Its molecular formula is C5H9ClO2 and its molecular weight is 136.58 g/mol. Its systematic (IUPAC) name is 2-methylpropyl carbonochloridate. Common synonyms include Chloroformic acid isobutyl ester and IBCF.

The material typically appears as a colourless liquid. Key physical data: a boiling point of 128.8 °C. Keep containers tightly closed in a cool, well-ventilated area away from heat and ignition sources. It carries the GHS signal word “Danger” with 7 hazard statements. Review the Safety Data Sheet before use.

Typical applications include protein and peptide research and organic synthesis. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 100 mL and 500 mL, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Protein & peptide research
Organic synthesis

Industries

Specifications & identifiers

Chemical identifiers
Product name	Isobutyl chloroformate, 98%
Catalogue No.	VQ-009142
CAS Number	543-27-1
IUPAC name	2-methylpropyl carbonochloridate
Molecular formula	C₅H₉ClO₂
Molecular weight	136.58 g/mol
Exact mass	136.0291
Grade	Synthesis
Purity / assay	98%
HSN code	29159090
InChIKey	YOETUEMZNOLGDB-UHFFFAOYSA-N
SMILES	CC(C)COC(=O)Cl
PubChem CID	62365

Physical properties
Physical form	Liquid
Appearance	Colourless liquid
Boiling point	128.8 °C
LogP (XLogP3)	2.8
H-bond donors / acceptors	0 / 2
TPSA	26.3 Å²
Synonyms	Chloroformic acid isobutyl ester, IBCF, 2-Methylpropyl chloroformate, Isobutyl chlorocarbonate, Chlorocarbonic acid isobutyl ester, Formic acid, chloro-, isobutyl ester, isobutyl carbonochloridate, Isobutylchloroformate, i-Butyl chloroformate, Isobutyl chloridocarbonate, CJC-1293 TFA Salt Hydrate (>90%), isobutylchlorformate

Safety & hazard information (GHS)

Flammable

Corrosive

Toxic

Harmful / irritant

Signal word: Danger

Hazard statements

H226Flammable liquid and vapor
H290May be corrosive to metals
H302Harmful if swallowed
H314Causes severe skin burns and eye damage
H318Causes serious eye damage
H331Toxic if inhaled
H335May cause respiratory irritation

Precautionary statements: P210, P233, P234, P240, P241, P242, P243, P260, P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P301 + P330 + P331, P302 + P361 + P354, P303 + P361 + P353, P304 + P340, P305 + P354 + P338, P316, P317, P319, P321

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Isobutyl chloroformate, 98%?

The CAS Registry Number of Isobutyl chloroformate, 98% is 543-27-1. It is also known as Chloroformic acid isobutyl ester, IBCF, 2-Methylpropyl chloroformate.

What is the molecular formula and molecular weight of Isobutyl chloroformate, 98%?

Isobutyl chloroformate, 98% has the molecular formula C5H9ClO2 and a molecular weight of 136.58 g/mol. Its IUPAC name is 2-methylpropyl carbonochloridate.

Which grade and pack sizes of Isobutyl chloroformate, 98% can I order?

We supply Isobutyl chloroformate, 98% in Synthesis (98%) grade, in 100 mL, 500 mL packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Isobutyl chloroformate, 98%?

Yes. Every lot of Isobutyl chloroformate, 98% is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Isobutyl chloroformate, 98% be shipped internationally?

Yes. Isobutyl chloroformate, 98% is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.