Busulfan

About Busulfan

Busulfan is a high-purity reference standard of Busulfan carrying the CAS registry number 55-98-1. Its molecular formula is C6H14O6S2 and its molecular weight is 246.3 g/mol. Systematically, it is named 4-methylsulfonyloxybutyl methanesulfonate. It is also known as Sulphabutin or Sulfabutin.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

As a reference sample of Busulfan, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Busulfan is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Busulfan

View every impurity, metabolite and intermediate we list for Busulfan.

Busulfan impurities

Specifications & identifiers

Chemical identifiers
Product name	Busulfan
Catalogue No.	VQ-021940
CAS Number	55-98-1
IUPAC name	4-methylsulfonyloxybutyl methanesulfonate
Molecular formula	C₆H₁₄O₆S₂
Molecular weight	246.3 g/mol
Exact mass	246.0232
Grade	Reference Standard
HSN code	38229090
InChIKey	COVZYZSDYWQREU-UHFFFAOYSA-N
SMILES	CS(=O)(=O)OCCCCOS(=O)(=O)C
PubChem CID	2478

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.5
H-bond donors / acceptors	0 / 6
TPSA	104 Å²
Synonyms	Sulphabutin, Sulfabutin, Mablin, Mielucin, Mielevcin, 1,4-Dimesyloxybutane, 1,4-Butanediol, dimethanesulfonate, 1,4-Dimethanesulfonoxybutane, Tetramethylene dimethane sulfonate, 1,4-Dimethylsulfonyloxybutane, 1,4-Bis(methanesulfonoxy)butane, 1,4-Butanediol dimethylsulfonate

Safety & hazard information (GHS)

Toxic

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H300Fatal if swallowed
H301Toxic if swallowed
H310Fatal in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H330Fatal if inhaled
H335May cause respiratory irritation
H340May cause genetic defects
H350May cause cancer
H360May damage fertility or the unborn child
H373May causes damage to organs through prolonged or repeated exposure

Precautionary statements: P203, P260, P261, P262, P264, P264 + P265, P270, P271, P280, P284, P301 + P316, P302 + P352, P304 + P340, P305 + P351 + P338, P316, P318, P319, P320, P321, P330, P332 + P317, P337 + P317, P361 + P364, P362 + P364

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Busulfan?

The CAS Registry Number of Busulfan is 55-98-1. It is also known as Sulphabutin, Sulfabutin, Mablin.

What is the molecular formula and molecular weight of Busulfan?

Busulfan has the molecular formula C6H14O6S2 and a molecular weight of 246.3 g/mol. Its IUPAC name is 4-methylsulfonyloxybutyl methanesulfonate.

What is Busulfan used for?

Busulfan is supplied as a characterised reference material related to Busulfan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Busulfan can I order?

We supply Busulfan in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Busulfan?

Yes. Every lot of Busulfan is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Busulfan be shipped internationally?

Yes. Busulfan is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.