Angustifoline

About Angustifoline

Angustifoline is an API impurity reference standard carrying the CAS registry number 550-43-6. With the molecular formula C14H22N2O, it has a molar mass of 234.34 g/mol. Systematically, it is named (1S,2R,9S,10S)-10-prop-2-enyl-7,11-diazatricyclo[7.3.1.02,7]tridecan-6-one. Alternative names: Angustifoline hydrochloride and Angustifolinehydrochloride.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 4 hazard statements. Review the Safety Data Sheet before use.

This the parent drug substance impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Specifications & identifiers

Chemical identifiers
Product name	Angustifoline
Catalogue No.	VQ-027294
CAS Number	550-43-6
IUPAC name	(1S,2R,9S,10S)-10-prop-2-enyl-7,11-diazatricyclo[7.3.1.02,7]tridecan-6-one
Molecular formula	C₁₄H₂₂N₂O
Molecular weight	234.34 g/mol
Exact mass	234.1732
Grade	Reference Standard
HSN code	38229090
InChIKey	VTIPIBIDDZPDAV-ZDEQEGDKSA-N
SMILES	C=CC[C@H]1[C@H]2C[C@@H](CN1)[C@H]3CCCC(=O)N3C2
PubChem CID	12306807

Physical properties
Physical form	Solid
LogP (XLogP3)	1.4
H-bond donors / acceptors	1 / 2
TPSA	32.3 Å²
Synonyms	(1S,2R,9S,10S)-10-prop-2-enyl-7,11-diazatricyclo(7.3.1.02,7)tridecan-6-one, Mixture of (-)-Angustifoline and Isoangustifoline, Angustifoline hydrochloride, Angustifolinehydrochloride, (1S,4S,5S,11AR)-4-allyldecahydro-8H-1,5-methanopyrido[1,2-a][1,5]diazocin-8-one

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302+H312+H332Harmful if swallowed, in contact with skin or if inhaled
H302Harmful if swallowed
H312Harmful in contact with skin
H332Harmful if inhaled

Precautionary statements: P261, P264, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P317, P321, P330, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Angustifoline?

The CAS Registry Number of Angustifoline is 550-43-6. It is also known as (1S,2R,9S,10S)-10-prop-2-enyl-7,11-diazatricyclo(7.3.1.02,7)tridecan-6-one, Mixture of (-)-Angustifoline and Isoangustifoline, Angustifoline hydrochloride.

What is the molecular formula and molecular weight of Angustifoline?

Angustifoline has the molecular formula C14H22N2O and a molecular weight of 234.34 g/mol. Its IUPAC name is (1S,2R,9S,10S)-10-prop-2-enyl-7,11-diazatricyclo[7.3.1.02,7]tridecan-6-one.

Which grade and pack sizes of Angustifoline can I order?

We supply Angustifoline in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Angustifoline?

Yes. Every lot of Angustifoline is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Angustifoline be shipped internationally?

Yes. Angustifoline is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.