5-Ethoxy-2-Mercaptobenzimidazole

About 5-Ethoxy-2-Mercaptobenzimidazole

5-Ethoxy-2-Mercaptobenzimidazole is an impurity of Afobazole carrying the CAS registry number 55489-15-1. With the molecular formula C9H10N2OS, it has a molar mass of 194.26 g/mol. The IUPAC name is 5-ethoxy-1,3-dihydrobenzimidazole-2-thione. It is also known as 5-Ethoxy-1H-benzo[d]imidazole-2-thiol or 5-ethoxy-1H-benzimidazole-2-thiol.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Afobazole to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer 5-Ethoxy-2-Mercaptobenzimidazole in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Afobazole

View every impurity, metabolite and intermediate we list for Afobazole.

Afobazole impurities

Specifications & identifiers

Chemical identifiers
Product name	5-Ethoxy-2-Mercaptobenzimidazole
Catalogue No.	VQ-035278
CAS Number	55489-15-1
IUPAC name	5-ethoxy-1,3-dihydrobenzimidazole-2-thione
Molecular formula	C₉H₁₀N₂OS
Molecular weight	194.26 g/mol
Exact mass	194.0514
Grade	Reference Standard
HSN code	38229090
InChIKey	WUSCBOFBIYZVCQ-UHFFFAOYSA-N
SMILES	CCOC1=CC2=C(C=C1)NC(=S)N2
PubChem CID	790793

Physical properties
Physical form	Solid
LogP (XLogP3)	1.5
H-bond donors / acceptors	2 / 2
TPSA	65.4 Å²
Synonyms	5-Ethoxy-1H-benzo[d]imidazole-2-thiol, 5-ethoxy-1H-benzimidazole-2-thiol, 5-ethoxy-1H-1,3-benzodiazole-2-thiol, 5-ethoxybenzimidazole-2-thiol, 5-ethoxy-1H-benzo[d]imidazole-2(3H)-thione, 2H-Benzimidazole-2-thione, 5-ethoxy-1,3-dihydro-, 6-ethoxy-1H-1,3-benzodiazole-2-thiol, 2-mercapto-5-ethoxybenzimidazole, 5-Ethoxy-2-benzimidazolethiol, 5-ethoxybenzimidazoline-2-thione, 6-Ethoxy-1H-benzo[d]imidazole-2-thiol, 5-Ethoxy-1,3-dihydro-2H-1,3-benzimidazole-2-thione

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 5-Ethoxy-2-Mercaptobenzimidazole?

The CAS Registry Number of 5-Ethoxy-2-Mercaptobenzimidazole is 55489-15-1. It is also known as 5-Ethoxy-1H-benzo[d]imidazole-2-thiol, 5-ethoxy-1H-benzimidazole-2-thiol, 5-ethoxy-1H-1,3-benzodiazole-2-thiol.

What is the molecular formula and molecular weight of 5-Ethoxy-2-Mercaptobenzimidazole?

5-Ethoxy-2-Mercaptobenzimidazole has the molecular formula C9H10N2OS and a molecular weight of 194.26 g/mol. Its IUPAC name is 5-ethoxy-1,3-dihydrobenzimidazole-2-thione.

What is 5-Ethoxy-2-Mercaptobenzimidazole used for?

5-Ethoxy-2-Mercaptobenzimidazole is supplied as a characterised reference material related to Afobazole. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 5-Ethoxy-2-Mercaptobenzimidazole can I order?

We supply 5-Ethoxy-2-Mercaptobenzimidazole in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 5-Ethoxy-2-Mercaptobenzimidazole?

Yes. Every lot of 5-Ethoxy-2-Mercaptobenzimidazole is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 5-Ethoxy-2-Mercaptobenzimidazole be shipped internationally?

Yes. 5-Ethoxy-2-Mercaptobenzimidazole is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.