N-Nitroso Desmethyldiphenhydramine

Name: N-Nitroso Desmethyldiphenhydramine
Brand: Vaqora Chemicals
SKU: VQ-022406

About N-Nitroso Desmethyldiphenhydramine

N-Nitroso Desmethyldiphenhydramine (CAS 55855-43-1) is a nitrosamine impurity of Dimenhydrinate offered by Vaqora Chemicals. Its molecular formula is C16H18N2O2 and its molecular weight is 270.33 g/mol. Systematically, it is named N-(2-benzhydryloxyethyl)-N-methylnitrous amide. It is also known as N-Nitroso Diphenhydramine.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

It is used as a reference standard for trace-level detection and quantitation of nitrosamine impurities by LC-MS/MS or GC-MS, supporting nitrosamine risk assessments for Dimenhydrinate, method validation (AMV) and regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, N-Nitroso Desmethyldiphenhydramine is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Nitrosamine risk assessment
Trace LC-MS/MS quantitation
Method validation (AMV)
Regulatory submissions

Industries

Related to Dimenhydrinate

View every impurity, metabolite and intermediate we list for Dimenhydrinate.

Dimenhydrinate impurities

Specifications & identifiers

Chemical identifiers
Product name	N-Nitroso Desmethyldiphenhydramine
Catalogue No.	VQ-022406
CAS Number	55855-43-1
IUPAC name	N-(2-benzhydryloxyethyl)-N-methylnitrous amide
Molecular formula	C₁₆H₁₈N₂O₂
Molecular weight	270.33 g/mol
Exact mass	270.1368
Grade	Reference Standard
HSN code	38229090
InChIKey	AZLXCAYLZMGCFN-UHFFFAOYSA-N
SMILES	CN(CCOC(C1=CC=CC=C1)C2=CC=CC=C2)N=O
PubChem CID	85845033

Physical properties
Physical form	Solid
LogP (XLogP3)	3.2
H-bond donors / acceptors	0 / 4
TPSA	41.9 Å²
Synonyms	N-Nitroso N-Desmethyl Diphenhydramine (Mixture of isomers), N-Nitroso Diphenhydramine, 2-(Diphenylmethoxy)-N-methyl-N-nitrosoethanamine, N-(2-(benzhydryloxy)ethyl)-N-methylnitrous amide, Ethanamine, 2-(diphenylmethoxy)-N-methyl-N-nitroso-

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H351Suspected of causing cancer

Precautionary statements: P203, P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P318, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Nitroso Desmethyldiphenhydramine?

The CAS Registry Number of N-Nitroso Desmethyldiphenhydramine is 55855-43-1. It is also known as N-Nitroso N-Desmethyl Diphenhydramine (Mixture of isomers), N-Nitroso Diphenhydramine, 2-(Diphenylmethoxy)-N-methyl-N-nitrosoethanamine.

What is the molecular formula and molecular weight of N-Nitroso Desmethyldiphenhydramine?

N-Nitroso Desmethyldiphenhydramine has the molecular formula C16H18N2O2 and a molecular weight of 270.33 g/mol. Its IUPAC name is N-(2-benzhydryloxyethyl)-N-methylnitrous amide.

What is N-Nitroso Desmethyldiphenhydramine used for?

N-Nitroso Desmethyldiphenhydramine is supplied as a characterised reference material related to Dimenhydrinate. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Nitroso Desmethyldiphenhydramine can I order?

We supply N-Nitroso Desmethyldiphenhydramine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Nitroso Desmethyldiphenhydramine?

Yes. Every lot of N-Nitroso Desmethyldiphenhydramine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Nitroso Desmethyldiphenhydramine be shipped internationally?

Yes. N-Nitroso Desmethyldiphenhydramine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.