Doxorubicinolone

About Doxorubicinolone

Doxorubicinolone is a process intermediate or related compound of Daunorubicin carrying the CAS registry number 56149-23-6. Formula C21H20O9, molecular weight 416.4 g/mol. The IUPAC name is (7S,9S)-9-[(1S)-1,2-dihydroxyethyl]-6,7,9,11-tetrahydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione. Alternative names: 4'-Deoxydoxorubicinol 7-deoxyaglycone and 4-Dol-done.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Process chemists and analysts use it when developing synthetic routes to Daunorubicin, tracking process-related impurities and validating analytical methods. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Daunorubicin

View every impurity, metabolite and intermediate we list for Daunorubicin.

Daunorubicin impurities

Specifications & identifiers

Chemical identifiers
Product name	Doxorubicinolone
Catalogue No.	VQ-047972
CAS Number	56149-23-6
IUPAC name	(7S,9S)-9-[(1S)-1,2-dihydroxyethyl]-6,7,9,11-tetrahydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione
Molecular formula	C₂₁H₂₀O₉
Molecular weight	416.4 g/mol
Exact mass	416.1107
InChIKey	CGVVIRBOJFDFBH-FPQVQZPGSA-N
SMILES	COC1=CC=CC2=C1C(=O)C3=C(C4=C(C[C@](C[C@@H]4O)([C@H](CO)O)O)C(=C3C2=O)O)O
PubChem CID	124320

Physical properties
Physical form	Solid
LogP (XLogP3)	1.7
H-bond donors / acceptors	6 / 9
TPSA	165 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Doxorubicinolone?

The CAS Registry Number of Doxorubicinolone is 56149-23-6. It is also known as 4'-Deoxydoxorubicinol 7-deoxyaglycone, 4-Dol-done, Doxorubicinol aglycone.

What is the molecular formula and molecular weight of Doxorubicinolone?

Doxorubicinolone has the molecular formula C21H20O9 and a molecular weight of 416.4 g/mol. Its IUPAC name is (7S,9S)-9-[(1S)-1,2-dihydroxyethyl]-6,7,9,11-tetrahydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione.

What is Doxorubicinolone used for?

Doxorubicinolone is supplied as a characterised reference material related to Daunorubicin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Doxorubicinolone can I order?

We supply Doxorubicinolone, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Doxorubicinolone?

Yes. Every lot of Doxorubicinolone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Doxorubicinolone be shipped internationally?

Yes. We export Doxorubicinolone worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.