3,6-Bis(hydroxymethyl)-2,5-piperazinedione

Name: 3,6-Bis(hydroxymethyl)-2,5-piperazinedione
Brand: Vaqora Chemicals
SKU: VQ-029959

About 3,6-Bis(hydroxymethyl)-2,5-piperazinedione

Vaqora Chemicals supplies 3,6-Bis(hydroxymethyl)-2,5-piperazinedione, a metabolite or degradation product of Cycloserine registered under CAS number 5625-41-2. Its molecular formula is C6H10N2O4 and its molecular weight is 174.15 g/mol. Its systematic (IUPAC) name is 3,6-bis(hydroxymethyl)piperazine-2,5-dione. It is also known as cyclo-serylserine or 2,5-Piperazinedione,3,6-bis(hydroxymethyl)-.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Cycloserine, as well as in QC testing and ANDA/DMF documentation. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 3,6-Bis(hydroxymethyl)-2,5-piperazinedione in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling
Fine chemical synthesis

Industries

Related to Cycloserine

View every impurity, metabolite and intermediate we list for Cycloserine.

Cycloserine impurities

Specifications & identifiers

Chemical identifiers
Product name	3,6-Bis(hydroxymethyl)-2,5-piperazinedione
Catalogue No.	VQ-029959
CAS Number	5625-41-2
IUPAC name	3,6-bis(hydroxymethyl)piperazine-2,5-dione
Molecular formula	C₆H₁₀N₂O₄
Molecular weight	174.15 g/mol
Exact mass	174.0641
Grade	Reference Standard
HSN code	38229090
InChIKey	SUWGHSHLNOADHI-UHFFFAOYSA-N
SMILES	C(C1C(=O)NC(C(=O)N1)CO)O
PubChem CID	138542

Physical properties
Physical form	Solid
LogP (XLogP3)	-1.5
H-bond donors / acceptors	4 / 4
TPSA	98.7 Å²
Synonyms	cyclo-serylserine, 2,5-Piperazinedione,3,6-bis(hydroxymethyl)-, 2,5-Piperazinedione, 3,6-bis(hydroxymethyl)-, 3,6-Bis(hydroxymethyl)-3,6-dihydropyrazine-2,5-diol, rac-(3S,6R)-3,6-Bis(hydroxymethyl)piperazine-2,5-dione, 2,5-Piperazinedione,3,6-bis(hydroxymethyl)-(6CI,7CI,8CI,9CI)

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 3,6-Bis(hydroxymethyl)-2,5-piperazinedione?

The CAS Registry Number of 3,6-Bis(hydroxymethyl)-2,5-piperazinedione is 5625-41-2. It is also known as cyclo-serylserine, 2,5-Piperazinedione,3,6-bis(hydroxymethyl)-, 2,5-Piperazinedione, 3,6-bis(hydroxymethyl)-.

What is the molecular formula and molecular weight of 3,6-Bis(hydroxymethyl)-2,5-piperazinedione?

3,6-Bis(hydroxymethyl)-2,5-piperazinedione has the molecular formula C6H10N2O4 and a molecular weight of 174.15 g/mol. Its IUPAC name is 3,6-bis(hydroxymethyl)piperazine-2,5-dione.

What is 3,6-Bis(hydroxymethyl)-2,5-piperazinedione used for?

3,6-Bis(hydroxymethyl)-2,5-piperazinedione is supplied as a characterised reference material related to Cycloserine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 3,6-Bis(hydroxymethyl)-2,5-piperazinedione can I order?

We supply 3,6-Bis(hydroxymethyl)-2,5-piperazinedione in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 3,6-Bis(hydroxymethyl)-2,5-piperazinedione?

Yes. Every lot of 3,6-Bis(hydroxymethyl)-2,5-piperazinedione is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 3,6-Bis(hydroxymethyl)-2,5-piperazinedione be shipped internationally?

Yes. 3,6-Bis(hydroxymethyl)-2,5-piperazinedione is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.