5,6-Dihydrouridine

Name: 5,6-Dihydrouridine
Brand: Vaqora Chemicals
SKU: VQ-042765

About 5,6-Dihydrouridine

5,6-Dihydrouridine (CAS 5627-05-4) is an impurity of Uridine offered by Vaqora Chemicals. Formula C9H14N2O6, molecular weight 246.22 g/mol. Its systematic (IUPAC) name is 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3-diazinane-2,4-dione. Common synonyms include Dihydrouridine and Hydrouracil, 1-beta-D-ribofuranosyl-.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Warning” with 6 hazard statements. Review the Safety Data Sheet before use.

This Uridine impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 5,6-Dihydrouridine is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Uridine

View every impurity, metabolite and intermediate we list for Uridine.

Uridine impurities

Specifications & identifiers

Chemical identifiers
Product name	5,6-Dihydrouridine
Catalogue No.	VQ-042765
CAS Number	5627-05-4
IUPAC name	1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3-diazinane-2,4-dione
Molecular formula	C₉H₁₄N₂O₆
Molecular weight	246.22 g/mol
Exact mass	246.0852
Grade	Reference Standard
HSN code	38229090
InChIKey	ZPTBLXKRQACLCR-XVFCMESISA-N
SMILES	C1CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O
PubChem CID	94312

Physical properties
Physical form	Solid
LogP (XLogP3)	-2.1
H-bond donors / acceptors	4 / 6
TPSA	119 Å²
Synonyms	Dihydrouridine, Hydrouracil, 1-beta-D-ribofuranosyl-, 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl)-1,3-diazinane-2,4-dione, 2,4(1H,3H)-Pyrimidinedione, dihydro-1-beta-D-ribofuranosyl-, 3,4-Dihydrouridine, Hydrouracil, 1-.beta.-D-ribofuranosyl-, 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-hydroxy-1,3-diazinan-2-one, 2,4(1H,3H)-Pyrimidinedione, dihydro-1-.beta.-D-ribofuranosyl-, dihydro-, 1-beta-D-ribofuranosylhydrouracil

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 5,6-Dihydrouridine?

The CAS Registry Number of 5,6-Dihydrouridine is 5627-05-4. It is also known as Dihydrouridine, Hydrouracil, 1-beta-D-ribofuranosyl-, 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl)-1,3-diazinane-2,4-dione.

What is the molecular formula and molecular weight of 5,6-Dihydrouridine?

5,6-Dihydrouridine has the molecular formula C9H14N2O6 and a molecular weight of 246.22 g/mol. Its IUPAC name is 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3-diazinane-2,4-dione.

What is 5,6-Dihydrouridine used for?

5,6-Dihydrouridine is supplied as a characterised reference material related to Uridine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 5,6-Dihydrouridine can I order?

We supply 5,6-Dihydrouridine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 5,6-Dihydrouridine?

Yes. Every lot of 5,6-Dihydrouridine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 5,6-Dihydrouridine be shipped internationally?

Yes. 5,6-Dihydrouridine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.