Des-Hydroxy Amino Triclosan

About Des-Hydroxy Amino Triclosan

Des-Hydroxy Amino Triclosan is an impurity of Triclosan carrying the CAS registry number 56966-52-0. The compound has the formula C12H8Cl3NO, corresponding to a molecular weight of 288.6 g/mol. Its systematic (IUPAC) name is 5-chloro-2-(2,4-dichlorophenoxy)aniline. Common synonyms include 2,4,4'-Trichloro-2'-aminodiphenyl ether and 5-Chloro-2-(2',4'-dichlorophenoxy)aniline.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Triclosan to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Des-Hydroxy Amino Triclosan is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Triclosan

View every impurity, metabolite and intermediate we list for Triclosan.

Triclosan impurities

Specifications & identifiers

Chemical identifiers
Product name	Des-Hydroxy Amino Triclosan
Catalogue No.	VQ-042674
CAS Number	56966-52-0
IUPAC name	5-chloro-2-(2,4-dichlorophenoxy)aniline
Molecular formula	C₁₂H₈Cl₃NO
Molecular weight	288.6 g/mol
Exact mass	286.9671
Grade	Reference Standard
HSN code	38229090
InChIKey	SOOLDKUMSVNBIW-UHFFFAOYSA-N
SMILES	C1=CC(=C(C=C1Cl)N)OC2=C(C=C(C=C2)Cl)Cl
PubChem CID	92602

Physical properties
Physical form	Solid
LogP (XLogP3)	4.7
H-bond donors / acceptors	1 / 2
TPSA	35.3 Å²
Synonyms	2,4,4'-Trichloro-2'-aminodiphenyl ether, Benzenamine, 5-chloro-2-(2,4-dichlorophenoxy)-, 5-Chloro-2-(2',4'-dichlorophenoxy)aniline, 2,4,4'-Trichloro-2-aminodiphenyl ether, 5-chloro-2-(2,4-dichlorophenoxy)-benzenamine

Safety & hazard information (GHS)

Environmental hazard

Signal word: Warning

Hazard statements

H410Very toxic to aquatic life with long lasting effects

Precautionary statements: P273, P391, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Des-Hydroxy Amino Triclosan?

The CAS Registry Number of Des-Hydroxy Amino Triclosan is 56966-52-0. It is also known as 2,4,4'-Trichloro-2'-aminodiphenyl ether, Benzenamine, 5-chloro-2-(2,4-dichlorophenoxy)-, 5-Chloro-2-(2',4'-dichlorophenoxy)aniline.

What is the molecular formula and molecular weight of Des-Hydroxy Amino Triclosan?

Des-Hydroxy Amino Triclosan has the molecular formula C12H8Cl3NO and a molecular weight of 288.6 g/mol. Its IUPAC name is 5-chloro-2-(2,4-dichlorophenoxy)aniline.

What is Des-Hydroxy Amino Triclosan used for?

Des-Hydroxy Amino Triclosan is supplied as a characterised reference material related to Triclosan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Des-Hydroxy Amino Triclosan can I order?

We supply Des-Hydroxy Amino Triclosan in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Des-Hydroxy Amino Triclosan?

Yes. Every lot of Des-Hydroxy Amino Triclosan is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Des-Hydroxy Amino Triclosan be shipped internationally?

Yes. Des-Hydroxy Amino Triclosan is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.