Physostigmine

Name: Physostigmine
Brand: Vaqora Chemicals
SKU: VQ-041464

About Physostigmine

Physostigmine (CAS 57-47-6) is a high-purity reference standard of Physostigmine offered by Vaqora Chemicals. Formula C15H21N3O2, molecular weight 275.35 g/mol. The IUPAC name is [(3aR,8bS)-3,4,8b-trimethyl-2,3a-dihydro-1H-pyrrolo[2,3-b]indol-7-yl] N-methylcarbamate. It is also known as Eserine or Physostol.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Danger” with 2 hazard statements. Review the Safety Data Sheet before use.

As a reference sample of Physostigmine, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Physostigmine is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Physostigmine

View every impurity, metabolite and intermediate we list for Physostigmine.

Physostigmine impurities

Specifications & identifiers

Chemical identifiers
Product name	Physostigmine
Catalogue No.	VQ-041464
CAS Number	57-47-6
IUPAC name	[(3aR,8bS)-3,4,8b-trimethyl-2,3a-dihydro-1H-pyrrolo[2,3-b]indol-7-yl] N-methylcarbamate
Molecular formula	C₁₅H₂₁N₃O₂
Molecular weight	275.35 g/mol
Exact mass	275.1634
Grade	Reference Standard
HSN code	38229090
InChIKey	PIJVFDBKTWXHHD-HIFRSBDPSA-N
SMILES	C[C@@]12CCN([C@@H]1N(C3=C2C=C(C=C3)OC(=O)NC)C)C
PubChem CID	5983

Physical properties
Physical form	Solid
LogP (XLogP3)	0.7
H-bond donors / acceptors	1 / 4
TPSA	44.8 Å²
Synonyms	Eserine, Physostol, Esromiotin, Ezerin, Calabarine, Fysostigmin, Erserine, cogmine, eserin, Eserolein, methylcarbamate (ester), MCV 4484

Safety & hazard information (GHS)

Toxic

Signal word: Danger

Hazard statements

H300Fatal if swallowed
H330Fatal if inhaled

Precautionary statements: P260, P264, P270, P271, P284, P301 + P316, P304 + P340, P316, P320, P321, P330, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Physostigmine?

The CAS Registry Number of Physostigmine is 57-47-6. It is also known as Eserine, Physostol, Esromiotin.

What is the molecular formula and molecular weight of Physostigmine?

Physostigmine has the molecular formula C15H21N3O2 and a molecular weight of 275.35 g/mol. Its IUPAC name is [(3aR,8bS)-3,4,8b-trimethyl-2,3a-dihydro-1H-pyrrolo[2,3-b]indol-7-yl] N-methylcarbamate.

What is Physostigmine used for?

Physostigmine is supplied as a characterised reference material related to Physostigmine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Physostigmine can I order?

We supply Physostigmine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Physostigmine?

Yes. Every lot of Physostigmine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Physostigmine be shipped internationally?

Yes. Physostigmine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.