6-Desacetyl Palbociclib

About 6-Desacetyl Palbociclib

6-Desacetyl Palbociclib is a metabolite or degradation product of Palbociclib carrying the CAS registry number 571190-22-2 with a typical assay of 99.72%. Its molecular formula is C22H27N7O and its molecular weight is 405.5 g/mol. The IUPAC name is 8-cyclopentyl-5-methyl-2-[(5-piperazin-1-yl-2-pyridinyl)amino]pyrido[2,3-d]pyrimidin-7-one. Alternative names: Palbociclib-1 and Palbociclib-010.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Analytical teams use this compound to identify metabolites and degradants of Palbociclib, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 6-Desacetyl Palbociclib is dispatched with a Certificate of Analysis (COA) to destinations worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Palbociclib

View every impurity, metabolite and intermediate we list for Palbociclib.

Palbociclib impurities

Specifications & identifiers

Chemical identifiers
Product name	6-Desacetyl Palbociclib
Catalogue No.	VQ-007091
CAS Number	571190-22-2
Other CAS	571189-66-7
IUPAC name	8-cyclopentyl-5-methyl-2-[(5-piperazin-1-yl-2-pyridinyl)amino]pyrido[2,3-d]pyrimidin-7-one
Molecular formula	C₂₂H₂₇N₇O
Molecular weight	405.5 g/mol
Exact mass	405.2277
Grade	Reference Standard
Purity / assay	99.72%
HSN code	38229090
InChIKey	HOXDMBXWILKORE-UHFFFAOYSA-N
SMILES	CC1=CC(=O)N(C2=NC(=NC=C12)NC3=NC=C(C=C3)N4CCNCC4)C5CCCC5
PubChem CID	5330281

Physical properties
Physical form	Solid
LogP (XLogP3)	1.9
H-bond donors / acceptors	2 / 7
TPSA	86.3 Å²
Synonyms	8-cyclopentyl-5-methyl-2-[(5-piperazin-1-ylpyridin-2-yl)amino]pyrido[2,3-d]pyrimidin-7-one, Palbociclib-1, Palbociclib-010, Pyrido-[2,3-d]-pyrimidin-7-one 38, 8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)a..., 8-cyclopentyl-5-methyl-2-[(5-piperazin-1-yl-2-pyridyl)amino]pyrido[2,3-d]pyrimidin-7-one

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 6-Desacetyl Palbociclib?

The CAS Registry Number of 6-Desacetyl Palbociclib is 571190-22-2. It is also known as 8-cyclopentyl-5-methyl-2-[(5-piperazin-1-ylpyridin-2-yl)amino]pyrido[2,3-d]pyrimidin-7-one, Palbociclib-1, Palbociclib-010.

What is the molecular formula and molecular weight of 6-Desacetyl Palbociclib?

6-Desacetyl Palbociclib has the molecular formula C22H27N7O and a molecular weight of 405.5 g/mol. Its IUPAC name is 8-cyclopentyl-5-methyl-2-[(5-piperazin-1-yl-2-pyridinyl)amino]pyrido[2,3-d]pyrimidin-7-one.

What is 6-Desacetyl Palbociclib used for?

6-Desacetyl Palbociclib is supplied as a characterised reference material related to Palbociclib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 6-Desacetyl Palbociclib can I order?

We supply 6-Desacetyl Palbociclib in Reference Standard (99.72%) grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 6-Desacetyl Palbociclib?

Yes. Every lot of 6-Desacetyl Palbociclib is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 6-Desacetyl Palbociclib be shipped internationally?

Yes. We export 6-Desacetyl Palbociclib worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.