Rhodanine-3-acetic acid

Name: Rhodanine-3-acetic acid
Brand: Vaqora Chemicals
SKU: VQ-030505

About Rhodanine-3-acetic acid

Vaqora Chemicals supplies Rhodanine-3-acetic acid, an impurity of Epalrestat registered under CAS number 5718-83-2. Formula C5H5NO3S2, molecular weight 191.2 g/mol. Systematically, it is named 2-(4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl)acetic acid. Common synonyms include 3-Rhodanineacetic Acid and (4-Oxo-2-thioxo-thiazolidin-3-yl)acetic acid.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

As a characterised impurity of Epalrestat, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Rhodanine-3-acetic acid in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Epalrestat

View every impurity, metabolite and intermediate we list for Epalrestat.

Epalrestat impurities

Specifications & identifiers

Chemical identifiers
Product name	Rhodanine-3-acetic acid
Catalogue No.	VQ-030505
CAS Number	5718-83-2
IUPAC name	2-(4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl)acetic acid
Molecular formula	C₅H₅NO₃S₂
Molecular weight	191.2 g/mol
Exact mass	190.9711
Grade	Reference Standard
HSN code	38229090
InChIKey	JGRMXPSUZIYDRR-UHFFFAOYSA-N
SMILES	C1C(=O)N(C(=S)S1)CC(=O)O
PubChem CID	79793

Physical properties
Physical form	Solid
LogP (XLogP3)	0.4
H-bond donors / acceptors	1 / 5
TPSA	115 Å²
Synonyms	3-Rhodanineacetic Acid, (4-Oxo-2-thioxo-thiazolidin-3-yl)acetic acid, 3-Thiazolidineacetic acid, 4-oxo-2-thioxo-, 3-(Carboxymethyl)rhodanine, Rhodanine-N-acetic acid, 2-(4-oxo-2-thioxothiazolidin-3-yl)acetic acid, 4-Oxo-2-thioxo-3-thiazolidinylacetic acid, N-(Carboxymethyl)rhodanine, 4-Oxo-2-thioxo-3-thiazolidineacetic acid, (4-Oxo-2-thioxo-1,3-thiazolidin-3-yl)acetic acid, 2-(4-oxo-2-thioxo-thiazolidin-3-yl)acetic acid

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Rhodanine-3-acetic acid?

The CAS Registry Number of Rhodanine-3-acetic acid is 5718-83-2. It is also known as 3-Rhodanineacetic Acid, (4-Oxo-2-thioxo-thiazolidin-3-yl)acetic acid, 3-Thiazolidineacetic acid, 4-oxo-2-thioxo-.

What is the molecular formula and molecular weight of Rhodanine-3-acetic acid?

Rhodanine-3-acetic acid has the molecular formula C5H5NO3S2 and a molecular weight of 191.2 g/mol. Its IUPAC name is 2-(4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl)acetic acid.

What is Rhodanine-3-acetic acid used for?

Rhodanine-3-acetic acid is supplied as a characterised reference material related to Epalrestat. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Rhodanine-3-acetic acid can I order?

We supply Rhodanine-3-acetic acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Rhodanine-3-acetic acid?

Yes. Every lot of Rhodanine-3-acetic acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Rhodanine-3-acetic acid be shipped internationally?

Yes. Rhodanine-3-acetic acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.