6-Mercaptopurine-9-beta-D-Ribofuranoside

About 6-Mercaptopurine-9-beta-D-Ribofuranoside

6-Mercaptopurine-9-beta-D-Ribofuranoside is an impurity of Mercaptopurine carrying the CAS registry number 574-25-4. Its molecular formula is C10H12N4O4S and its molecular weight is 284.29 g/mol. Systematically, it is named 9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-purine-6-thione. It is also known as 6-Mercaptopurine-9-β-D-Ribofuranoside or 6-Thioinosine.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Mercaptopurine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Mercaptopurine

View every impurity, metabolite and intermediate we list for Mercaptopurine.

Mercaptopurine impurities

Specifications & identifiers

Chemical identifiers
Product name	6-Mercaptopurine-9-beta-D-Ribofuranoside
Catalogue No.	VQ-032674
CAS Number	574-25-4
IUPAC name	9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-purine-6-thione
Molecular formula	C₁₀H₁₂N₄O₄S
Molecular weight	284.29 g/mol
Exact mass	284.0579
Grade	Reference Standard
HSN code	38229090
InChIKey	NKGPJODWTZCHGF-KQYNXXCUSA-N
SMILES	C1=NC(=S)C2=C(N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O
PubChem CID	676166

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.6
H-bond donors / acceptors	4 / 6
TPSA	144 Å²
Synonyms	6-Mercaptopurine-9-β-D-Ribofuranoside, 6-Thioinosine, Ribosyl-6-thiopurine, Mercaptopurine ribonucleoside, Mercaptopurine riboside, 6-Mercaptopurine ribonucleoside, 6H-Purine-6-thione, 1,9-dihydro-9-ribofuranosyl-, 9H-Purine-6(1H)-thione, 9-beta-D-ribofuranosyl-, Ribosyl-6-mercaptopurine, Riboside, 6-Mercaptopurine

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 6-Mercaptopurine-9-beta-D-Ribofuranoside?

The CAS Registry Number of 6-Mercaptopurine-9-beta-D-Ribofuranoside is 574-25-4. It is also known as 6-Mercaptopurine-9-β-D-Ribofuranoside, 6-Thioinosine, Ribosyl-6-thiopurine.

What is the molecular formula and molecular weight of 6-Mercaptopurine-9-beta-D-Ribofuranoside?

6-Mercaptopurine-9-beta-D-Ribofuranoside has the molecular formula C10H12N4O4S and a molecular weight of 284.29 g/mol. Its IUPAC name is 9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-purine-6-thione.

What is 6-Mercaptopurine-9-beta-D-Ribofuranoside used for?

6-Mercaptopurine-9-beta-D-Ribofuranoside is supplied as a characterised reference material related to Mercaptopurine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 6-Mercaptopurine-9-beta-D-Ribofuranoside can I order?

We supply 6-Mercaptopurine-9-beta-D-Ribofuranoside in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 6-Mercaptopurine-9-beta-D-Ribofuranoside?

Yes. Every lot of 6-Mercaptopurine-9-beta-D-Ribofuranoside is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 6-Mercaptopurine-9-beta-D-Ribofuranoside be shipped internationally?

Yes. 6-Mercaptopurine-9-beta-D-Ribofuranoside is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.