Methyl 2-Methyl-2-phenylpropanoate

About Methyl 2-Methyl-2-phenylpropanoate

Methyl 2-Methyl-2-phenylpropanoate is an impurity of Fexofenadine carrying the CAS registry number 57625-74-8. Formula C11H14O2, molecular weight 178.23 g/mol. It is also known as 2-methyl-2-phenyl-propionic acid methyl ester or Methyl 2,2-dimethyl-2-phenylacetate.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Fexofenadine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Methyl 2-Methyl-2-phenylpropanoate is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Fexofenadine

View every impurity, metabolite and intermediate we list for Fexofenadine.

Fexofenadine impurities

Specifications & identifiers

Chemical identifiers
Product name	Methyl 2-Methyl-2-phenylpropanoate
Catalogue No.	VQ-037251
CAS Number	57625-74-8
IUPAC name	methyl 2-methyl-2-phenylpropanoate
Molecular formula	C₁₁H₁₄O₂
Molecular weight	178.23 g/mol
Exact mass	178.0994
Grade	Reference Standard
HSN code	38229090
InChIKey	WITYUUTUSPKOAB-UHFFFAOYSA-N
SMILES	CC(C)(C1=CC=CC=C1)C(=O)OC
PubChem CID	143498

Physical properties
Physical form	Solid
LogP (XLogP3)	2.6
H-bond donors / acceptors	0 / 2
TPSA	26.3 Å²
Synonyms	Alpha α Dimethyl Phenyl Acetic Acid Methyl Ester, 2-methyl-2-phenyl-propionic acid methyl ester, Methyl 2,2-dimethyl-2-phenylacetate, Benzeneacetic acid, alpha,alpha-dimethyl-, methyl ester, Ethyl2,2-dimethylphenylacetate, alpha,alpha-d, 2-Methyl-2-phenylpropanoic acid methyl ester, methyl 2-methyl-2-phenylpropionate

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Methyl 2-Methyl-2-phenylpropanoate?

The CAS Registry Number of Methyl 2-Methyl-2-phenylpropanoate is 57625-74-8. It is also known as Alpha α Dimethyl Phenyl Acetic Acid Methyl Ester, 2-methyl-2-phenyl-propionic acid methyl ester, Methyl 2,2-dimethyl-2-phenylacetate.

What is the molecular formula and molecular weight of Methyl 2-Methyl-2-phenylpropanoate?

Methyl 2-Methyl-2-phenylpropanoate has the molecular formula C11H14O2 and a molecular weight of 178.23 g/mol. Its IUPAC name is methyl 2-methyl-2-phenylpropanoate.

What is Methyl 2-Methyl-2-phenylpropanoate used for?

Methyl 2-Methyl-2-phenylpropanoate is supplied as a characterised reference material related to Fexofenadine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Methyl 2-Methyl-2-phenylpropanoate can I order?

We supply Methyl 2-Methyl-2-phenylpropanoate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Methyl 2-Methyl-2-phenylpropanoate?

Yes. Every lot of Methyl 2-Methyl-2-phenylpropanoate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Methyl 2-Methyl-2-phenylpropanoate be shipped internationally?

Yes. We export Methyl 2-Methyl-2-phenylpropanoate worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.