Azelastine

Name: Azelastine
Brand: Vaqora Chemicals
SKU: VQ-029325

About Azelastine

Listed under CAS 58581-89-8, Azelastine is a high-purity reference standard of Azelastine available from Vaqora Chemicals. Its molecular formula is C22H24ClN3O and its molecular weight is 381.9 g/mol. Its systematic (IUPAC) name is 4-[(4-chlorophenyl)methyl]-2-(1-methylazepan-4-yl)phthalazin-1-one. Common synonyms include Vividrin akut Azelastin and rac-Azelastine.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Laboratories use this Azelastine standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Azelastine in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Azelastine

View every impurity, metabolite and intermediate we list for Azelastine.

Azelastine impurities

Specifications & identifiers

Chemical identifiers
Product name	Azelastine
Catalogue No.	VQ-029325
CAS Number	58581-89-8
IUPAC name	4-[(4-chlorophenyl)methyl]-2-(1-methylazepan-4-yl)phthalazin-1-one
Molecular formula	C₂₂H₂₄ClN₃O
Molecular weight	381.9 g/mol
Exact mass	381.1608
Grade	Reference Standard
HSN code	38229090
InChIKey	MBUVEWMHONZEQD-UHFFFAOYSA-N
SMILES	CN1CCCC(CC1)N2C(=O)C3=CC=CC=C3C(=N2)CC4=CC=C(C=C4)Cl
PubChem CID	2267

Physical properties
Physical form	Solid
LogP (XLogP3)	4.4
H-bond donors / acceptors	0 / 3
TPSA	35.9 Å²
Synonyms	4-(4-chlorobenzyl)-2-(1-methylazepan-4-yl)phthalazin-1(2H)-one, 4-(p-Chlorobenzyl)-2-(hexahydro-1-methyl-1H-azepin-4-yl)-1-(2H)-phthalazinone, 1(2H)-Phthalazinone, 4-((4-chlorophenyl)methyl)-2-(hexahydro-1-methyl-1H-azepin-4-yl)-, 4-[(4-chlorophenyl)methyl]-2-(1-methylazepan-4-yl)-1,2-dihydrophthalazin-1-one, 4-((4-chlorophenyl)methyl)-2-(1-methylazepan-4-yl)-1,2-dihydrophthalazin-1-one, Vividrin akut Azelastin, 4-(p-chlorobenzyl)-2-(N-methylperhydroazepinyl-(4))-1-(2H)-phthalazinone, 1(2H)-Phthalazinone,4-[(4-chlorophenyl)methyl]-2-(hexahydro-1-methyl-1H-azepin-4-yl)-, 4-[(4-chlorophenyl)methyl]-2-(1-methylazepan-4-yl)phthalazin-1(2H)-one, rac-Azelastine, 1(2H)-phthalazinone,4-[(4-chlorophenyl)methyl]-2-[(4s)-hexahydro-1-methyl-1h-azepin-4-yl]-

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H332Harmful if inhaled
H335May cause respiratory irritation
H351Suspected of causing cancer
H413May cause long lasting harmful effects to aquatic life

Precautionary statements: P203, P261, P264, P270, P271, P273, P280, P301 + P317, P302 + P352, P304 + P340, P317, P318, P319, P321, P330, P332 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Azelastine?

The CAS Registry Number of Azelastine is 58581-89-8. It is also known as 4-(4-chlorobenzyl)-2-(1-methylazepan-4-yl)phthalazin-1(2H)-one, 4-(p-Chlorobenzyl)-2-(hexahydro-1-methyl-1H-azepin-4-yl)-1-(2H)-phthalazinone, 1(2H)-Phthalazinone, 4-((4-chlorophenyl)methyl)-2-(hexahydro-1-methyl-1H-azepin-4-yl)-.

What is the molecular formula and molecular weight of Azelastine?

Azelastine has the molecular formula C22H24ClN3O and a molecular weight of 381.9 g/mol. Its IUPAC name is 4-[(4-chlorophenyl)methyl]-2-(1-methylazepan-4-yl)phthalazin-1-one.

What is Azelastine used for?

Azelastine is supplied as a characterised reference material related to Azelastine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Azelastine can I order?

We supply Azelastine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Azelastine?

Yes. Every lot of Azelastine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Azelastine be shipped internationally?

Yes. Azelastine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.