Proparacaine Hydrochloride

About Proparacaine Hydrochloride

Proparacaine Hydrochloride is a high-purity reference standard of Proparacaine carrying the CAS registry number 5875-06-9. With the molecular formula C16H27ClN2O3, it has a molar mass of 330.8 g/mol. Common synonyms include Proxymetacaine Hydrochloride and Proparacaine Hcl.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

As a reference sample of Proparacaine, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Proparacaine

View every impurity, metabolite and intermediate we list for Proparacaine.

Proparacaine impurities

Specifications & identifiers

Chemical identifiers
Product name	Proparacaine Hydrochloride
Catalogue No.	VQ-041720
CAS Number	5875-06-9
IUPAC name	2-(diethylamino)ethyl 3-amino-4-propoxybenzoate;hydrochloride
Molecular formula	C₁₆H₂₇ClN₂O₃
Molecular weight	330.8 g/mol
Exact mass	330.171
Grade	Reference Standard
HSN code	38229090
InChIKey	BFUUJUGQJUTPAF-UHFFFAOYSA-N
SMILES	CCCOC1=C(C=C(C=C1)C(=O)OCCN(CC)CC)N.Cl
PubChem CID	517321

Physical properties
Physical form	Solid
H-bond donors / acceptors	2 / 5
TPSA	64.8 Å²
Synonyms	Proxymetacaine Hydrochloride, Proparacaine Hcl, Ophthetic, Paracaine, Ak-taine, Keracaine, 2-(Diethylamino)ethyl 3-amino-4-propoxybenzoate monohydrochloride, proxymetacaine monohydrochloride, 2-(Diethylamino)ethyl 3-Amino-4-propoxybenzoate Hydrochloride, Alcaine, Ophthaine

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H332Harmful if inhaled

Precautionary statements: P261, P264, P264 + P265, P270, P271, P272, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P321, P330, P333 + P317, P337 + P317, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Proparacaine Hydrochloride?

The CAS Registry Number of Proparacaine Hydrochloride is 5875-06-9. It is also known as Proxymetacaine Hydrochloride, Proparacaine Hcl, Ophthetic.

What is the molecular formula and molecular weight of Proparacaine Hydrochloride?

Proparacaine Hydrochloride has the molecular formula C16H27ClN2O3 and a molecular weight of 330.8 g/mol.

What is Proparacaine Hydrochloride used for?

Proparacaine Hydrochloride is supplied as a characterised reference material related to Proparacaine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Proparacaine Hydrochloride can I order?

We supply Proparacaine Hydrochloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Proparacaine Hydrochloride?

Yes. Every lot of Proparacaine Hydrochloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Proparacaine Hydrochloride be shipped internationally?

Yes. Proparacaine Hydrochloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.