Cis-Permethric Acid

About Cis-Permethric Acid

Cis-Permethric Acid is an impurity of Permethrin carrying the CAS registry number 59042-49-8. Its molecular formula is C8H10Cl2O2 and its molecular weight is 209.07 g/mol. Its systematic (IUPAC) name is trans-(1S,3S)-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylic acid. It is also known as (+/-)-cis-Permethrinic acid or cis-Permethrinic Acid.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Permethrin to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Cis-Permethric Acid is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Permethrin

View every impurity, metabolite and intermediate we list for Permethrin.

Permethrin impurities

Specifications & identifiers

Chemical identifiers
Product name	Cis-Permethric Acid
Catalogue No.	VQ-033139
CAS Number	59042-49-8
IUPAC name	trans-(1S,3S)-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylic acid
Molecular formula	C₈H₁₀Cl₂O₂
Molecular weight	209.07 g/mol
Exact mass	208.0058
Grade	Reference Standard
HSN code	38229090
InChIKey	LLMLSUSAKZVFOA-INEUFUBQSA-N
SMILES	CC1([C@@H]([C@@H]1C(=O)O)C=C(Cl)Cl)C
PubChem CID	41507

Physical properties
Physical form	Solid
LogP (XLogP3)	3.3
H-bond donors / acceptors	1 / 2
TPSA	37.3 Å²
Synonyms	cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropane carboxylic acid, cis-3-(2,2-Dichloroethenyl)-2,2-dimethylcyclopropanecarboxylic acid, (1S,3S)-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylic acid, (1S,3S)-3-(2,2-Dichlorovinyl)-2,2-dimethylcyclopropane-1-carboxylic acid, (+/-)-cis-Permethrinic acid, cis-Permethrinic Acid, cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid, (1S,3S)-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylic acid, 1R-cis-Permethric acid, Cyclopropanecarboxylic acid, 3-(2,2-dichloroethenyl)-2,2-dimethyl-, cis-, Cyclopropanecarboxylic acid, 3-(2,2-dichloroethenyl)-2,2-dimethyl-, (1R,3R)-rel-, cis-DL-3-(2,2-Dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation

Precautionary statements: P264, P264 + P265, P280, P302 + P352, P305 + P351 + P338, P321, P332 + P317, P337 + P317, P362 + P364

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Cis-Permethric Acid?

The CAS Registry Number of Cis-Permethric Acid is 59042-49-8. It is also known as cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropane carboxylic acid, cis-3-(2,2-Dichloroethenyl)-2,2-dimethylcyclopropanecarboxylic acid, (1S,3S)-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylic acid.

What is the molecular formula and molecular weight of Cis-Permethric Acid?

Cis-Permethric Acid has the molecular formula C8H10Cl2O2 and a molecular weight of 209.07 g/mol. Its IUPAC name is trans-(1S,3S)-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylic acid.

What is Cis-Permethric Acid used for?

Cis-Permethric Acid is supplied as a characterised reference material related to Permethrin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Cis-Permethric Acid can I order?

We supply Cis-Permethric Acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Cis-Permethric Acid?

Yes. Every lot of Cis-Permethric Acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Cis-Permethric Acid be shipped internationally?

Yes. Cis-Permethric Acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.