5-Hydroxymebendazole

Name: 5-Hydroxymebendazole
Brand: Vaqora Chemicals
SKU: VQ-031745

About 5-Hydroxymebendazole

Vaqora Chemicals supplies 5-Hydroxymebendazole, a metabolite or degradation product of Mebendazole registered under CAS number 60254-95-7. Formula C16H15N3O3, molecular weight 297.31 g/mol. Its systematic (IUPAC) name is methyl N-[6-[hydroxy(phenyl)methyl]-1H-benzimidazol-2-yl]carbamate. It is also known as rac Dihydro Mebendazole or Mebendazole-5-hydroxy.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Mebendazole, as well as in QC testing and ANDA/DMF documentation. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer 5-Hydroxymebendazole in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling
Fine chemical synthesis

Industries

Related to Mebendazole

View every impurity, metabolite and intermediate we list for Mebendazole.

Mebendazole impurities

Specifications & identifiers

Chemical identifiers
Product name	5-Hydroxymebendazole
Catalogue No.	VQ-031745
CAS Number	60254-95-7
IUPAC name	methyl N-[6-[hydroxy(phenyl)methyl]-1H-benzimidazol-2-yl]carbamate
Molecular formula	C₁₆H₁₅N₃O₃
Molecular weight	297.31 g/mol
Exact mass	297.1113
Grade	Reference Standard
HSN code	38229090
InChIKey	IIQKUGXEGMZCLE-UHFFFAOYSA-N
SMILES	COC(=O)NC1=NC2=C(N1)C=C(C=C2)C(C3=CC=CC=C3)O
PubChem CID	43242

Physical properties
Physical form	Solid
LogP (XLogP3)	2.3
H-bond donors / acceptors	3 / 4
TPSA	87.2 Å²
Synonyms	methyl 5(6)-(alpha-hydroxyphenylmethyl)benzimidazole-2-carbamate, rac Dihydro Mebendazole, Mebendazole-5-hydroxy, Compound 86-162, Carbamic acid,(5-Hydroxyphenylmethyl)-1h-benzimidazol-2-yl, Carbamic acid, (5-hydroxyphenylmethyl)-1H-benzimidazol-2-yl-, 5-(alpha-Hydroxybenzyl)-2-benzimidazolecarbamic acid methyl ester, Carbamic acid, (5-alpha-hydroxyphenylmethyl-1H-benzimidazol-2-yl)-, methyl ester, methyl (5-(hydroxy(phenyl)methyl)-1H-benzo[d]imidazol-2-yl)carbamate, 2-BENZIMIDAZOLECARBAMIC ACID, 5-(alpha-HYDROXYBENZYL)-, METHYL ESTER, Methyl {6-[hydroxy(phenyl)methyl]-1H-1,3-benzimidazol-2-yl}carbamate, methyl N-{6-[hydroxy(phenyl)methyl]-1H-1,3-benzodiazol-2-yl}carbamate

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H361Suspected of damaging fertility or the unborn child

Precautionary statements: P203, P264, P270, P280, P301 + P317, P318, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 5-Hydroxymebendazole?

The CAS Registry Number of 5-Hydroxymebendazole is 60254-95-7. It is also known as methyl 5(6)-(alpha-hydroxyphenylmethyl)benzimidazole-2-carbamate, rac Dihydro Mebendazole, Mebendazole-5-hydroxy.

What is the molecular formula and molecular weight of 5-Hydroxymebendazole?

5-Hydroxymebendazole has the molecular formula C16H15N3O3 and a molecular weight of 297.31 g/mol. Its IUPAC name is methyl N-[6-[hydroxy(phenyl)methyl]-1H-benzimidazol-2-yl]carbamate.

What is 5-Hydroxymebendazole used for?

5-Hydroxymebendazole is supplied as a characterised reference material related to Mebendazole. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 5-Hydroxymebendazole can I order?

We supply 5-Hydroxymebendazole in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 5-Hydroxymebendazole?

Yes. Every lot of 5-Hydroxymebendazole is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 5-Hydroxymebendazole be shipped internationally?

Yes. 5-Hydroxymebendazole is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.