(4S)-4-(Chloromethyl)-2,2-dimethyl-1,3-dioxol… 60456-22-6

Name: (4S)-4-(Chloromethyl)-2,2-dimethyl-1,3-dioxolane
Brand: Vaqora Chemicals
SKU: VQ-040623

About (4S)-4-(Chloromethyl)-2,2-dimethyl-1,3-dioxolane

(4S)-4-(Chloromethyl)-2,2-dimethyl-1,3-dioxolane (CAS 60456-22-6) is an API impurity reference standard offered by Vaqora Chemicals. With the molecular formula C6H11ClO2, it has a molar mass of 150.6 g/mol. It is also known as (S)-(-)-3-Chloro-1,2-propanediol acetonide or (S)-3-chloro-1,2-propanediol acetonide.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

As a characterised impurity of the parent drug substance, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Specifications & identifiers

Chemical identifiers
Product name	(4S)-4-(Chloromethyl)-2,2-dimethyl-1,3-dioxolane
Catalogue No.	VQ-040623
CAS Number	60456-22-6
IUPAC name	(4S)-4-(chloromethyl)-2,2-dimethyl-1,3-dioxolane
Molecular formula	C₆H₁₁ClO₂
Molecular weight	150.6 g/mol
Exact mass	150.0448
Grade	Reference Standard
HSN code	38229090
InChIKey	BNPOTXLWPZOESZ-RXMQYKEDSA-N
SMILES	CC1(OC[C@H](O1)CCl)C
PubChem CID	6930483

Physical properties
Physical form	Solid
LogP (XLogP3)	1.1
H-bond donors / acceptors	0 / 2
TPSA	18.5 Å²
Synonyms	(S)-(-)-3-Chloro-1,2-propanediol acetonide, (S)-4-(chloromethyl)-2,2-dimethyl-1,3-dioxolane, (S)-3-chloro-1,2-propanediol acetonide, 4-(Chloromethyl)-2,2-dimethyl-1,3-dioxolane, (-)-, 1,3-Dioxolane, 4-(chloromethyl)-2,2-dimethyl-, (4S)-, (S)-4-Chloromethyl-2,2-dimethyl-1,3-dioxolane, (S)-(-)-4-(Chloromethyl)-2,2-dimethyl-1,3-dioxolane, (S)-(-)-4-chloromethyl-2,2-dimethyl-1,3-dioxolane, 1,3-Dioxolane, 4-(chloromethyl)-2,2-dimethyl-, (S)-, (S)-4-Chloromethyl-2,2-dimethyl-[1,3]dioxolane, (S)-(+)-4-(Chloromethyl)-2,2-dimethyl-1,3-dioxolane

Safety & hazard information (GHS)

Flammable

Corrosive

Toxic

Signal word: Danger

Hazard statements

H226Flammable liquid and vapor
H301Toxic if swallowed
H318Causes serious eye damage

Precautionary statements: P210, P233, P240, P241, P242, P243, P264, P264 + P265, P270, P280, P301 + P316, P303 + P361 + P353, P305 + P354 + P338, P317, P321, P330, P370 + P378, P403 + P235, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (4S)-4-(Chloromethyl)-2,2-dimethyl-1,3-dioxolane?

The CAS Registry Number of (4S)-4-(Chloromethyl)-2,2-dimethyl-1,3-dioxolane is 60456-22-6. It is also known as (S)-(-)-3-Chloro-1,2-propanediol acetonide, (S)-4-(chloromethyl)-2,2-dimethyl-1,3-dioxolane, (S)-3-chloro-1,2-propanediol acetonide.

What is the molecular formula and molecular weight of (4S)-4-(Chloromethyl)-2,2-dimethyl-1,3-dioxolane?

(4S)-4-(Chloromethyl)-2,2-dimethyl-1,3-dioxolane has the molecular formula C6H11ClO2 and a molecular weight of 150.6 g/mol. Its IUPAC name is (4S)-4-(chloromethyl)-2,2-dimethyl-1,3-dioxolane.

Which grade and pack sizes of (4S)-4-(Chloromethyl)-2,2-dimethyl-1,3-dioxolane can I order?

We supply (4S)-4-(Chloromethyl)-2,2-dimethyl-1,3-dioxolane in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (4S)-4-(Chloromethyl)-2,2-dimethyl-1,3-dioxolane?

Yes. Every lot of (4S)-4-(Chloromethyl)-2,2-dimethyl-1,3-dioxolane is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (4S)-4-(Chloromethyl)-2,2-dimethyl-1,3-dioxolane be shipped internationally?

Yes. (4S)-4-(Chloromethyl)-2,2-dimethyl-1,3-dioxolane is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.